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完成的 COVID-19 传染病三个阶段的 SEIR 序参量和特征向量:以 2020 年 1 月至 5 月泰国为例。

SEIR order parameters and eigenvectors of the three stages of completed COVID-19 epidemics: with an illustration for Thailand January to May 2020.

机构信息

Department of Psychology and Department of Physics, University of Connecticut, Storrs, CT 06269, United States of America.

Department of Physics, Faculty of Science, Kasetsart University, Bangkok, 10900, Thailand.

出版信息

Phys Biol. 2021 May 13;18(4). doi: 10.1088/1478-3975/abf426.

Abstract

By end of October 2020, the COVID-19 pandemic has taken a tragic toll of 1150 000 lives and this number is expected to increase. Despite the pandemic is raging in most parts of the world, in a few countries COVID-19 epidemics subsided due to successful implementations of intervention measures. A unifying perspective of the beginnings, middle stages, and endings of such completed COVID-19 epidemics is developed based on the order parameter and eigenvalue concepts of nonlinear physics, in general, and synergetics, in particular. To this end, a standard susceptible-exposed-infected-recovered (SEIR) epidemiological model is used. It is shown that COVID-19 epidemic outbreaks follow a suitably defined SEIR order parameter. Intervention measures switch the eigenvalue of the order parameter from a positive to a negative value, and in doing so, stabilize the COVID-19 disease-free state. The subsiding of COVID-19 epidemics eventually follows the remnant of the order parameter of the infection dynamical system. These considerations are illustrated for the COVID-19 epidemic in Thailand from January to May 2020. The decay of effective contact rates throughout the three epidemic stages is demonstrated. Evidence for the sign-switching of the dominant eigenvalue is given and the order parameter and its stage-3 remnant are identified. The presumed impacts of interventions measures implemented in Thailand are discussed in this context.

摘要

截至 2020 年 10 月底,COVID-19 大流行已造成 115 万人死亡,且这一数字预计还将增加。尽管 COVID-19 在世界大部分地区仍在肆虐,但在少数几个国家,由于干预措施的成功实施,COVID-19 疫情已得到控制。本文基于非线性物理学(特别是协同论)中的序参量和本征值的概念,针对已经结束的 COVID-19 疫情,发展出一种通用的疫情起始、中期和结束的分析视角。为此,我们采用了标准的易感-暴露-感染-恢复(SEIR)传染病模型。研究结果表明,COVID-19 疫情的爆发遵循一个适当定义的 SEIR 序参量。干预措施将序参量的本征值从正值切换为负值,从而使 COVID-19 无病状态稳定下来。最终,COVID-19 疫情的消退遵循感染动力学系统的序参量残余。本文以 2020 年 1 月至 5 月泰国的 COVID-19 疫情为例,对这些结论进行了说明。本文演示了在疫情的三个阶段中有效接触率的衰减。提供了主导本征值符号切换的证据,并识别了序参量及其第三阶段的残余。本文还在这一背景下讨论了泰国所采取的干预措施的影响。

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