Department of Cell & Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA
mSphere. 2021 Mar 31;6(2):e00241-21. doi: 10.1128/mSphere.00241-21.
Chelsey C. Spriggs works in the field of DNA viral entry with a specific interest in virus-host interactions. In this mSphere of Influence article, she reflects on how two papers, "The HCMV assembly compartment is a dynamic Golgi-derived MTOC that controls nuclear rotation and virus spread" (D. J. Procter, A. Banerjee, M. Nukui, K. Kruse, et al., Dev Cell 45:83-100.e7, 2018, https://doi.org/10.1016/j.devcel.2018.03.010) and "Cytoplasmic control of intranuclear polarity by human cytomegalovirus" (D. J. Procter, C. Furey, A. G. Garza-Gongora, S. T. Kosak, D. Walsh, Nature 587:109-114, 2020, https://doi.org/10.1038/s41586-020-2714-x), impacted her research by reinforcing the scientific value in using viruses to understand cell biology.
切尔西·C·斯普里格斯(Chelsey C. Spriggs)从事 DNA 病毒进入领域的工作,特别关注病毒-宿主相互作用。在这篇 mSphere 影响力文章中,她反思了两篇论文是如何影响她的研究的,这两篇论文分别是“CMV 组装隔室是一个动态的、源自高尔基体的 MTOC,它控制核旋转和病毒传播”(D. J. Procter、A. Banerjee、M. Nukui、K. Kruse 等人,《细胞》45:83-100.e7, 2018, https://doi.org/10.1016/j.devcel.2018.03.010)和“人巨细胞病毒通过细胞质控制核内极性”(D. J. Procter、C. Furey、A. G. Garza-Gongora、S. T. Kosak、D. Walsh,《自然》587:109-114, 2020, https://doi.org/10.1038/s41586-020-2714-x),这些论文通过强调使用病毒来理解细胞生物学的科学价值,对她的研究产生了影响。