IEEE Trans Biomed Eng. 2021 Nov;68(11):3308-3316. doi: 10.1109/TBME.2021.3070477. Epub 2021 Oct 19.
The emergence of in-body medical devices has provided a means of capturing physiological or diagnostic information and streaming this information outside of the body. Currently, electromagnetic-based communications make up the bulk of in-body medical device communication protocols. Traditional electromagnetic-based solutions are limited in their data rates and available power. Recently, ultrasound was investigated as a communication channel for through-tissue data transmission. To achieve real-time video streaming through tissue, data rates of ultrasound need to exceed 1 Mbps. In a previous study, we demonstrated ultrasound communications with data rates greater than 30 Mbps with two focused ultrasound transducers using a large footprint laboratory system through slabs of lossy tissues. While the form factor of the transmitter is also crucial, it is obvious that a large, focused transducer cannot fit within the size of a small in-body medical device. Several other challenges for achieving high-speed ultrasonic communication through tissue include strong reflections leading to multipath effects and attenuation. In this work, we demonstrate ultrasonic video communications using a mm-scale microcrystal transmitter with video streaming supplied by a camera connected to a Field Programmable Gate Array (FPGA). The signals were transmitted through a tissue-mimicking phantom and through the abdomen of a rabbit in vivo. The ultrasound signal was recorded by an array probe connected to a Verasonics Vantage system and decoded back to video. To improve the received signal quality, we combined the signal from multiple channels of the array probe. Orthogonal frequency division multiplexing (OFDM) modulation was used to reduce the receiver complexity under a strong multipath environment.
体内医疗设备的出现为捕获生理或诊断信息并将这些信息传输到体外提供了一种手段。目前,基于电磁的通信构成了体内医疗设备通信协议的大部分。传统的基于电磁的解决方案在数据速率和可用功率方面受到限制。最近,超声被研究作为一种用于组织内数据传输的通信信道。为了实现组织内的实时视频流,超声需要超过 1Mbps 的数据速率。在之前的一项研究中,我们使用大型实验室系统通过损耗组织的平板展示了使用两个聚焦超声换能器的数据速率大于 30Mbps 的超声通信。虽然发射器的外形因素也很关键,但显然,一个大的、聚焦的换能器无法适应小型体内医疗设备的尺寸。实现组织内高速超声通信的其他一些挑战包括导致多径效应和衰减的强反射。在这项工作中,我们使用具有毫米级尺寸的微晶体发射器展示了超声视频通信,视频流由连接到现场可编程门阵列(FPGA)的摄像机提供。信号通过组织模拟体模和活体兔子的腹部传输。通过连接到 Verasonics Vantage 系统的阵列探头记录超声信号,并对其进行解码以恢复视频。为了提高接收信号质量,我们组合了阵列探头多个通道的信号。正交频分复用(OFDM)调制用于在强多径环境下降低接收器的复杂性。