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儿童单纯性阑尾炎的非手术治疗:前瞻性队列研究的 5 年长期随访。

Non-operative treatment of children with simple appendicitis: long-term follow-up (5 years) in a prospective cohort study.

机构信息

Department of Paediatric Surgery, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

Paediatric Clinical Research Office, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.

出版信息

Br J Surg. 2021 Apr 5;108(3):e99-e100. doi: 10.1093/bjs/znaa052.

DOI:10.1093/bjs/znaa052
PMID:33793731
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10364911/
Abstract

Long-term results after non-operative treatment for children with simple appendicitis seem promising, possibly avoiding appendicectomy in 70 per cent of children after a median follow-up of 5 years. The need for delayed appendicectomy more than 2 years after the initial treatment is rare (0–5 per cent) and no complications occurred past 1 year, including children who underwent delayed appendicectomy.

摘要

对于单纯性阑尾炎患儿采用非手术治疗的长期疗效似乎较为乐观,在中位随访 5 年后,70%的患儿可能无需进行阑尾切除术。初始治疗后 2 年以上行延迟性阑尾切除术的需求很少见(0-5%),且 1 年后无任何并发症发生,包括接受延迟性阑尾切除术的患儿。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b5/10364911/3b902c467772/znaa052f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b5/10364911/3b902c467772/znaa052f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b5/10364911/3b902c467772/znaa052f1.jpg

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Br J Surg. 2021 Apr 5;108(3):e99-e100. doi: 10.1093/bjs/znaa052.
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本文引用的文献

1
Nonoperative Treatment Versus Appendectomy for Acute Nonperforated Appendicitis in Children: Five-year Follow Up of a Randomized Controlled Pilot Trial.非手术治疗与阑尾切除术治疗儿童急性非穿孔阑尾炎的对比:一项随机对照试验的 5 年随访结果。
Ann Surg. 2020 Jun;271(6):1030-1035. doi: 10.1097/SLA.0000000000003646.
2
Outcome of initially nonoperative treatment for acute simple appendicitis in children.儿童急性单纯性阑尾炎初始非手术治疗的结果
J Pediatr Surg. 2018 Sep;53(9):1849-1854. doi: 10.1016/j.jpedsurg.2017.12.012. Epub 2017 Dec 24.
3
Comparison of Antibiotic Therapy and Appendectomy for Acute Uncomplicated Appendicitis in Children: A Meta-analysis.
儿童急性单纯性阑尾炎抗生素治疗与阑尾切除术的比较:一项荟萃分析。
JAMA Pediatr. 2017 May 1;171(5):426-434. doi: 10.1001/jamapediatrics.2017.0057.
4
Long-term outcomes of operative versus nonoperative treatment for uncomplicated appendicitis.非复杂性阑尾炎手术治疗与非手术治疗的长期结果
J Pediatr Surg. 2015 Nov;50(11):1893-7. doi: 10.1016/j.jpedsurg.2015.07.008. Epub 2015 Jul 14.
5
Initial antibiotic treatment for acute simple appendicitis in children is safe: Short-term results from a multicenter, prospective cohort study.儿童急性单纯性阑尾炎的初始抗生素治疗是安全的:一项多中心前瞻性队列研究的短期结果
Surgery. 2015 May;157(5):916-23. doi: 10.1016/j.surg.2015.01.008. Epub 2015 Mar 16.
6
Ultrasound-based decision making in the treatment of acute appendicitis in children.基于超声的儿童急性阑尾炎治疗决策
J Pediatr Surg. 2004 Sep;39(9):1316-20. doi: 10.1016/j.jpedsurg.2004.05.011.