Department of Respiratory Pathophysiology, Monaldi-Cotugno Hospital, Naples.
Monaldi Arch Chest Dis. 2021 Apr 1;91(3). doi: 10.4081/monaldi.2021.1739.
We present three cases of patients affected by severe SARS-CoV-2-related pneumonia treated with a low molecular weight heparin for prevention or treatment of pulmonary embolism, who presented a major bleed, in particular an ileopsoas haematoma that caused severe anaemia; in one case it was fatal. In the recent outbreak of novel coronavirus infection, significantly abnormal coagulation parameters in SARS-CoV-2 infection occur very often, but complications in the opposite direction such as bleeding diathesis are very rare. In these cases, there are different levels of gravity: for one patient the major bleed required the anticoagulant therapy to be stopped until bleeding stabilized, one patient needed interventional radiology and one patient died.
我们报告了 3 例因严重 SARS-CoV-2 相关肺炎而接受低分子肝素预防或治疗肺栓塞的患者，他们均出现大出血，特别是髂腰肌血肿导致严重贫血；其中 1 例为致命性的。在新型冠状病毒感染的最近一次爆发中，SARS-CoV-2 感染中经常出现显著异常的凝血参数，但出血倾向等相反方向的并发症非常罕见。在这些情况下，严重程度不同：1 例大出血患者需要停止抗凝治疗，直到出血稳定；1 例患者需要介入放射学治疗，1 例患者死亡。
