Li Ruo-Fei, Zhu Cheng-Gen, Xu Cheng-Bo, Guo Qing-Lan, Shi Jian-Gong
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
J Asian Nat Prod Res. 2021 Jun;23(6):513-526. doi: 10.1080/10286020.2021.1906658. Epub 2021 Apr 1.
Seven new monoterpene alkaloids (-), along with 18 known analogues, were isolated from an aqueous decoction of the hook-bearing stems of (Gou-teng). Their structures were determined by spectroscopic data analysis and electronic circular dichroism (ECD) calculations. Compound is the first monoterpene 22-norindoloquinolizidine alkaloid with a ketene unit, while and are unusual indoloquinolizidine alkaloids having an oxazinane ring.[Formula: see text].
从钩藤带钩茎的水煎液中分离出7个新的单萜生物碱（-）以及18个已知类似物。通过光谱数据分析和电子圆二色（ECD）计算确定了它们的结构。化合物是首个具有烯酮单元的单萜22-去甲吲哚喹嗪类生物碱，而和是具有恶嗪烷环的不寻常吲哚喹嗪类生物碱。[分子式：见原文]
