在意大利中部，在 SARS-CoV-2 感染大流行期间可以安全地进行胃肠内窥镜检查。
Gastrointestinal endoscopy can be safely performed during pandemic SARS-CoV-2 infection in Central Italy.
机构信息
Department of Surgical-Medical Sciences and Translational Medicine, Digestive and Liver Disease Unit, Sant'Andrea Hospital, Sapienza University of Rome.
General Management, Sant'Andrea Hospital.
出版信息
Eur J Gastroenterol Hepatol. 2021 Dec 1;33(1S Suppl 1):e505-e512. doi: 10.1097/MEG.0000000000002155.
OBJECTIVES
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly contagious; gastrointestinal endoscopies are considered risky procedures for the endoscopy staff. Data on the SARS-CoV-2-exposure/infection rate of gastrointestinal endoscopy staff is scarce. This study aimed to assess the SARS-CoV-2-exposure/infection rate among gastrointestinal endoscopists/nurses performing gastrointestinal endoscopies before and after the adoption of specific prevention measures.
PATIENTS AND METHODS
Cross-sectional study in a teaching hospital (Rome, Central Italy) on retrospective data (9 March-15 April 2020) of consecutive gastrointestinal endoscopies, characteristics of procedures, patients and endoscopy staff, SARS-CoV-2-exposure/positivity of patients and staff before and after adoption of prevention measures. Exposed staff tested for SARS-CoV-2 by nasopharyngeal swabs(RNA-PCR) and serology.
RESULTS
A total of 130 gastrointestinal endoscopies were performed in 130 patients (age 66 ± 14 years, 51% women, 51% inpatients, 56.9% lower). A total of 12 (9.2%) patients were SARS-CoV-2-positive and 14(10.8%) had a high risk of potential infection. Of the endoscopy staff (n = 16, 5 endoscopists, 8 nurses and 3 residents), 14 (87.5%) were exposed to SARS-CoV-2-infected and 16 (100%) to potentially infected patients. 3/5 and 5/5 endoscopists were exposed to actual and potential, 1/3 and 3/3 residents to actual and potential and 8/8 nurses to actual and potential infection, respectively. None of the staff was found to be infected with SARS-CoV-2. None experienced fever or any other suspicious symptoms of coronavirus disease 2019. Before the adoption of prevention measures, more endoscopists/nurses were in the endoscopy room than after (3.5 ± 0.6 vs. 2.1 ± 0.3, P < 0.0001).
CONCLUSIONS
Despite supposed high infection risk, gastrointestinal endoscopies may be safe for the endoscopy staff during the SARS-CoV-2 pandemic.
目的
严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）具有高度传染性；胃肠内镜检查被认为是对内镜医护人员有风险的操作。关于 SARS-CoV-2 暴露/感染率的胃肠内镜医护人员的数据很少。本研究旨在评估在采用特定预防措施前后，进行胃肠内镜检查的胃肠内镜医师/护士的 SARS-CoV-2 暴露/感染率。
患者和方法
这是一家教学医院（意大利罗马中部）的横断面研究，回顾性分析了 2020 年 3 月 9 日至 4 月 15 日期间连续进行的胃肠内镜检查、操作特点、患者和内镜医护人员、采用预防措施前后患者和医护人员的 SARS-CoV-2 暴露/阳性率。暴露的医护人员通过鼻咽拭子（RNA-PCR）和血清学检测进行 SARS-CoV-2 检测。
结果
共对 130 名患者（年龄 66±14 岁，51%为女性，51%为住院患者，56.9%为下消化道）进行了 130 例胃肠内镜检查。共有 12 例（9.2%）患者 SARS-CoV-2 阳性，14 例（10.8%）有潜在感染的高风险。在 16 名内镜医护人员（5 名内镜医师、8 名护士和 3 名住院医师）中，14 名（87.5%）接触过 SARS-CoV-2 感染患者，16 名（100%）接触过有潜在感染风险的患者。3/5 名内镜医师和 5/5 名住院医师接触过实际和潜在感染患者，1/3 名住院医师和 3/3 名住院医师接触过实际和潜在感染患者，8/8 名护士接触过实际和潜在感染患者。没有医护人员被发现感染 SARS-CoV-2。没有人出现发热或任何其他可疑的 2019 年冠状病毒病症状。在采用预防措施之前，进入内镜室的内镜医师/护士人数多于之后（3.5±0.6 与 2.1±0.3，P＜0.0001）。
结论
尽管感染风险较高，但在 SARS-CoV-2 大流行期间，胃肠内镜检查对内镜医护人员可能是安全的。
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