ENT Department of Fattouma Bourguiba, University Hospital of Monastir, Monastir, Tunisia.
Research Unit "Quality and Security of care" (UR12SP41), University of Monastir, Monastir, Tunisia.
Pan Afr Med J. 2020 Dec 22;37:369. doi: 10.11604/pamj.2020.37.369.26909. eCollection 2020.
Castleman's disease is a rare pathology, poorly understood. It is considered as a lymphoproliferative disorder, described for the first time in 1954, which may be confused with other causes of lymphadenopathy. We report in this paper the case of a young women presenting with left latero-cervical lymphadenopathy. All the investigations were negative except a large high-vascularized level II cervical lymphadenopathy. We performed a cervicotomy. The extemporaneous histological exam was non-contributive. We decided to perform a complete level II and III left cervical lymphadenectomy. The diagnosis of unicentric Castleman's disease was confirmed based on the final histological study of the specimen, and the absence of other cervical and extra-cervical lymphadenopathy. The patient is free of recurrence at the time of reporting this article.
血管滤泡性淋巴结增生症是一种罕见的疾病，其发病机制尚未完全阐明。它被认为是一种淋巴组织增生性疾病，于 1954 年首次被描述，可能与其他淋巴结病的病因相混淆。我们在此报告一例年轻女性，表现为左侧颈侧部淋巴结病。除了 II 区大血管化的淋巴结肿大外，所有检查均为阴性。我们进行了颈淋巴结切除术。术中快速病理检查无明确结果。我们决定进行 II 区和 III 区左侧颈淋巴结清扫术。根据标本的最终组织学研究和无其他颈部和颈部外淋巴结病，诊断为单中心血管滤泡性淋巴结增生症。在报告本文时，患者无复发。
