克兰费尔特综合征患者的雄激素性脱发：病例报告及文献综述
Androgenetic Alopecia in a Patient with Klinefelter Syndrome: Case Report and Literature Review.
作者信息
Alsalhi Waleed, Tosti Antonella
机构信息
Department of Dermatology, College of Medicine, Majmaah University, Al-Majmaah, Saudi Arabia.
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.
出版信息
Skin Appendage Disord. 2021 Feb;7(2):135-138. doi: 10.1159/000512224. Epub 2020 Dec 7.
Abstract
INTRODUCTION
Klinefelter syndrome (KS) is defined as (a chromosomal disorder in which males have an extra X chromosome). KS presents clinically with signs of androgen deficiency including low testosterone. Androgenetic alopecia (AGA) develops as a response of the hair follicle cells to androgens in individuals with genetic predisposition.
CASE PRESENTATION
We describe a 17-year-old male patient with KS who developed AGA with a Ludwig pattern.
CONCLUSION
Our patient had a good response to oral minoxidil, finasteride, and low-level light therapy.
摘要
引言
克兰费尔特综合征（KS）被定义为（一种男性多一条X染色体的染色体疾病）。KS临床上表现为雄激素缺乏的症状，包括睾酮水平低。雄激素性脱发（AGA）是毛囊细胞对有遗传易感性个体体内雄激素产生的反应。
病例报告
我们描述了一名17岁患有KS的男性患者，其出现了路德维希型AGA。
结论
我们的患者对口服米诺地尔、非那雄胺和低能量光疗反应良好。
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