在扫频源光学相干断层扫描血管造影成像的息肉样脉络膜血管病变中，1型黄斑新生血管形成的息肉被替代。

Replacement of polyps with type 1 macular neovascularization in polypoidal choroidal vasculopathy imaged with swept source OCT angiography.

作者信息

Shen Mengxi, Bo Qiyu, Song Minlu, Jiang Xiaoshuang, Yehoshua Zohar, Gregori Giovanni, Sun Xiaodong, Wang Fenghua, Rosenfeld Philip J

机构信息

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

出版信息

Am J Ophthalmol Case Rep. 2021 Mar 11;22:101057. doi: 10.1016/j.ajoc.2021.101057. eCollection 2021 Jun.

PURPOSE

To investigate the morphological changes of polyps in eyes with polypoidal choroidal vasculopathy (PCV) after treatment with vascular endothelial growth factor (VEGF) inhibitors using swept source optical coherence tomography angiography (SS-OCTA).

OBSERVATIONS

Following anti-VEGF therapy, polyps were found to evolve into typical type 1 macular neovascularization (MNV) in five eyes. In all of these five eyes, a polypoidal lesion was detected adjacent to a serous or hemorrhagic retinal pigment epithelial detachment (PED).

CONCLUSIONS AND IMPORTANCE

Polypoidal lesions in PCV can evolve into typical type 1 MNV. This morphological evolution suggests that these polyps are clusters of tangled vessels that can proliferate into a more typical neovascular pattern, and this evolution may be facilitated by being adjacent to a PED. Since this morphological appearance could be associated with a better prognosis, SS-OCTA might be helpful in identifying cases of transformed polyps that may be associated with a decreased risk for vision loss.