Department of Veterinary Anatomy, Faculty of Veterinary Medicine, Universitas Airlangga, Mulyorejo Campus C Surabaya, East Java 60115, Indonesia.
Laboratory of Anatomy and Clinical Pathology, Faculty of Veterinary Medicine, Universitas Airlangga, Mulyorejo Campus C Surabaya, East Java 60115, Indonesia.
Trop Biomed. 2021 Mar 1;38(1):57-61. doi: 10.47665/tb.38.1.010.
Timor deer (Cervus timorensis) at Surabaya zoo, Indonesia, that were found to be naturally infected with Fasciola, showed elevated level of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP). Of a total of 75 deer examined, 12 (25%) of the 47 adult deer and 8 (29%) of the 28 juvenile deer were found to be infected with fascioliasis, as evidenced by the shedding of the parasite eggs. The level of ALT, AST and ALP were significantly elevated (p<0.05) in all the infected deer. Only Fasciolainfected deer showed elevated serum liver enzyme. Deer with elevated enzyme level show a trend that positively correspond with higher Egg per gram of feces (EPG). The average size of the parasite eggs at 169.0±11.1 × 96.0±3.5μm, correspond well with that of Fasciola gigantica. No other trematode eggs were observed besides that of F. gigantica. There was no significant difference in the enzyme profile between the two sexes in both the infected and the uninfected group. This is the first report of the elevation of serum liver enzyme in Timor deer that is associated with not only fascioliasis and also correspond positively with the EPG.
印度尼西亚泗水动物园的蹄鹿（Cervus timorensis）自然感染片形吸虫，表现出血清丙氨酸氨基转移酶（ALT）、天冬氨酸氨基转移酶（AST）和碱性磷酸酶（ALP）水平升高。在检查的 75 只鹿中，47 只成年鹿中有 12 只（25%）和 28 只幼鹿中有 8 只（29%）被证实患有片形吸虫病，这是通过寄生虫卵的脱落证明的。所有感染的鹿的 ALT、AST 和 ALP 水平均显著升高（p<0.05）。只有感染片形吸虫的鹿显示出血清肝酶升高。酶水平升高的鹿显示出与粪便每克卵（EPG）更高呈正相关的趋势。寄生虫卵的平均大小为 169.0±11.1×96.0±3.5μm，与巨型片形吸虫的大小相符。除了巨型片形吸虫外，未观察到其他吸虫卵。在感染和未感染组中，两性之间的酶谱在两组中均无显著差异。这是首例蹄鹿血清肝酶升高与片形吸虫病相关的报告，并且与 EPG 呈正相关。
