Wishart H Y, Williams T I, Smith G
Br J Anaesth. 1977 Dec;49(12):1259-63. doi: 10.1093/bja/49.12.1259.
Ninety patients (age range 49--99 yr) with a fracture of the neck of the femur were anaesthetized by a technique using halothane in oxygen in a closed circuit, halothane and 66% nitrous oxide in oxygen in a Magill circuit or artificial ventilation with 66% nitrous oxide in oxygen ("IPPV group"). In all three groups, there was a small decrease in PaO2 from an overall mean of 9.07 kPa before operation to 8.13 kPa at 60 min after anaesthesia. There was no significant difference between the groups in respect of the decrease; it was concluded that closed-circuit halothane in oxygen anaesthesia for this type of surgery was not accompanied by a significant degree of absorption collapse.
90例股骨颈骨折患者(年龄范围49 - 99岁),采用以下麻醉技术:在闭合回路中使用氟烷与氧气混合麻醉、在Magill回路中使用氟烷和66%氧化亚氮与氧气混合麻醉或使用66%氧化亚氮与氧气进行人工通气(“间歇正压通气组”)。在所有三组中,动脉血氧分压(PaO2)略有下降,从术前总体平均值9.07kPa降至麻醉后60分钟时的8.13kPa。各组之间在下降幅度方面无显著差异;得出的结论是,这种类型手术采用闭合回路氟烷与氧气麻醉不会伴有显著程度的吸收性肺萎陷。