Adams A P, Freedman A, Henville J D
Br J Ophthalmol. 1979 Mar;63(3):204-10. doi: 10.1136/bjo.63.3.204.
Measurement of intraocular pressure (IOP) by applanation tonometry in 23 patients undergoing lens extraction showed that a normocapnic general anaesthetic technique with controlled ventilation of the lungs (IPPV) reliably reduced the IOP by 50% for the duration of the operative period. This was not associated with large falls in systemic arterial pressure which are often a feature of spontaneously breathing halothane anaesthesia for eye surgery. Normocapnia and IPPV were easy to achieve by use of the single-limb coaxial Bain anaesthetic breathing circuit in conjunction with an electrically driven, small, and inexpensive ventilator while the anesthetic mixture of 33% oxygen and 0.5% halothane in nitrous oxide was delivered at a rate of 70 ml/kg body weight per minute.
对23例接受晶状体摘除术的患者进行压平眼压计测量眼压(IOP),结果显示,在手术期间,采用肺控制通气的正常碳酸血症全身麻醉技术(间歇正压通气,IPPV)可可靠地使眼压降低50%。这与全身动脉压大幅下降无关,而全身动脉压大幅下降通常是眼外科手术中自发呼吸的氟烷麻醉的一个特征。通过使用单管同轴贝恩麻醉呼吸回路并结合电动、小型且廉价的呼吸机,很容易实现正常碳酸血症和IPPV,同时以每分钟70 ml/kg体重的速率输送33%氧气和0.5%氟烷与氧化亚氮的麻醉混合气体。