Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Department of Family Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
J Affect Disord. 2021 May 15;287:174-181. doi: 10.1016/j.jad.2021.02.017. Epub 2021 Feb 5.
Obesity is a known risk factor for various chronic conditions, as well as mental health disorders. However, there have been few studies on weight change and mental health according to obesity. This study was performed to elucidate the association between weight changes and mental health according to obesity in middle-aged women.
Data from the Korean National Health and Nutrition Examination Survey (2014, 2016, 2018), which included 3953 women aged 40 to 59, were used in this study. After excluding those who had chronic conditions possibly affecting weight change, 2964 women were included in the study. The associations between weight changes and mental health, including perceived stress, depressed mood surveyed by the patient health questionnaire-9(PHQ-9), and current depressive disorder were analyzed.
Weight change in non-obese and obese women was associated with poorer mental health, including perceived stress and depressed mood (p<0.05), although the significance disappeared in covariates-adjusted analysis in obese women. Both non-obese and obese women with weight gain had higher perceived stress than women with weight loss, while in the PHQ-9 scores, higher scores were observed in non-obese women with weight gain, and in obese women with weight loss.
Our study could not define causality because this was a cross-sectional study. And the information on body weight change was obtained by self-reported questionnaires.
Our study suggested that in relatively healthy middle-aged Korean women, weight change was a significant factor associated with mental health, but obesity itself was not.
肥胖是各种慢性疾病以及心理健康障碍的已知危险因素。然而，关于肥胖与心理健康之间的体重变化的研究较少。本研究旨在阐明中年女性肥胖与体重变化和心理健康之间的关系。
本研究使用了韩国国家健康和营养检查调查（2014 年、2016 年和 2018 年）的数据，该调查包括 3953 名年龄在 40 至 59 岁的女性。在排除可能影响体重变化的慢性疾病后，共有 2964 名女性纳入研究。分析了体重变化与心理健康之间的关系，包括通过患者健康问卷-9（PHQ-9）调查的感知压力和抑郁情绪以及当前的抑郁障碍。
非肥胖和肥胖女性的体重变化与较差的心理健康有关，包括感知压力和抑郁情绪（p<0.05），尽管在肥胖女性的协变量调整分析中，这种相关性消失了。体重增加的非肥胖和肥胖女性的感知压力均高于体重减轻的女性，而 PHQ-9 评分中，体重增加的非肥胖女性和体重减轻的肥胖女性的评分较高。
由于本研究是一项横断面研究，因此我们的研究无法确定因果关系。而且，体重变化的信息是通过自我报告的问卷获得的。
我们的研究表明，在相对健康的韩国中年女性中，体重变化是与心理健康相关的重要因素，但肥胖本身并不是。
