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A random forest algorithm-based prediction model for moderate to severe acute postoperative pain after orthopedic surgery under general anesthesia.基于随机森林算法的全麻骨科手术后中重度急性术后疼痛预测模型。
BMC Anesthesiol. 2023 Nov 6;23(1):361. doi: 10.1186/s12871-023-02328-1.
2
Development and testing of a random forest-based machine learning model for predicting events among breast cancer patients with a poor response to neoadjuvant chemotherapy.基于随机森林的机器学习模型的开发和测试,用于预测新辅助化疗反应不良的乳腺癌患者的事件。
Eur J Med Res. 2023 Sep 30;28(1):394. doi: 10.1186/s40001-023-01361-7.
3
The efficacy of perioperative antibiotic therapy in adenotonsillectomy children.腺样体扁桃体切除术患儿围手术期抗生素治疗的疗效。
Eur Arch Otorhinolaryngol. 2024 Jan;281(1):267-272. doi: 10.1007/s00405-023-08244-x. Epub 2023 Sep 22.
4
Application of machine learning algorithm in predicting distant metastasis of T1 gastric cancer.机器学习算法在预测 T1 期胃癌远处转移中的应用。
Sci Rep. 2023 Apr 7;13(1):5741. doi: 10.1038/s41598-023-31880-6.
5
Discovery and Validation of Traditional Chinese and Western Medicine Combination Antirheumatoid Arthritis Drugs Based on Machine Learning (Random Forest Model).基于机器学习(随机森林模型)的抗风湿关节炎中西药组合药物的发现和验证。
Biomed Res Int. 2023 Feb 15;2023:6086388. doi: 10.1155/2023/6086388. eCollection 2023.
6
Multicentre clinical study of haemorrhage after coblation tonsillectomy in children: a prospective study protocol.多中心临床研究:儿童等离子扁桃体切除术后出血:前瞻性研究方案。
BMJ Open. 2023 Jan 10;13(1):e063401. doi: 10.1136/bmjopen-2022-063401.
7
Does infection play a role in post-tonsillectomy haemorrhage? A narrative review.感染在扁桃体切除术后出血中起作用吗?一篇叙述性综述。
J Laryngol Otol. 2023 Jul;137(7):710-717. doi: 10.1017/S0022215122002547. Epub 2022 Dec 13.
8
Supervised machine learning and associated algorithms: applications in orthopedic surgery.监督式机器学习及相关算法:在骨科手术中的应用
Knee Surg Sports Traumatol Arthrosc. 2023 Apr;31(4):1196-1202. doi: 10.1007/s00167-022-07181-2. Epub 2022 Oct 12.
9
Utility of the Pediatric Bleeding Questionnaire in Predicting Posttonsillectomy Bleeding.小儿出血问卷在预测扁桃体切除术后出血中的效用
Otolaryngol Head Neck Surg. 2022 Sep;167(3):576-582. doi: 10.1177/01945998211061474. Epub 2021 Nov 23.
10
Risk Factors for Postoperative Bleeding after Adenoidectomy.腺样体切除术后出血的危险因素
Children (Basel). 2021 Mar 21;8(3):242. doi: 10.3390/children8030242.

基于随机森林模型预测儿童扁桃体切除术后出血率

[Prediction of hemorrhage rate after tonsil surgery in children based on random forest model].

作者信息

Xu Hongming, Qiu Shuyao, Wang Jinxia, Han Fugen, Xia Zhongfang, Ni Liyan, Ma Jing, Chen Chunguang, Gao Xingqiang, Zhang Junmei, Liu Haixia, Liu Haibing, Yao Hongbing, Zhuang Qianger, Song Wei, Zhao Sijun, Zhang Mingjun, Liu Dabo, Li Xiaoyan

机构信息

Department of Otorhinolaryngology Head and Neck Surgery,Shanghai Children's Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai,200062,China.

Department of Pediatric Otorhinolaryngology,Shenzhen Hospital,Southern Medical University.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Oct;38(10):883-890. doi: 10.13201/j.issn.2096-7993.2024.10.001.

DOI:10.13201/j.issn.2096-7993.2024.10.001
PMID:39390924
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11839569/
Abstract

Hemorrhage after tonsil surgery in children is a serious and potentially life-threatening complication. The purpose of this study was to establish a risk warning model for hemorrhage after tonsil surgery in children through a national multi-center retrospective study, providing a basis for hierarchical management after tonsil surgery in children. Stratified sampling was performed on 8 854 children who underwent tonsillectomy under general anesthesia from 15 research centers in different provinces from January 15, 2022 to May 15, 2023. The sample size of this study was 2 724 cases, including 1 096 males and 1 628 females. Children were divided into bleeding and non-bleeding groups according to whether or not they had bleeding after surgery. The random forest algorithm was used to build a risk warning model. By continuously exploring the optimized model, the accuracy of predicting the postoperative bleeding rate of tonsils in children was improved, and the prediction effectiveness of the model was verified by ten-fold cross-validation. Among 2 724 children, 117 had postoperative bleeding after tonsillectomy, with a bleeding rate of 4.30%. The model constructed by the random forest algorithm for the training set was verified in the test set, and the obtained prediction accuracy was 98.72%, the recall rate was 78.95%, and the area under the ROC curve AUC was 0.96. Although the recall rate of the random forest model needs to be improved, the overall accuracy is quite excellent. It can effectively avoid misjudging positive cases as negative cases. It is a useful tool that can be used to predict the postoperative bleeding rate of tonsils and clinical medical decision-making, laying a good foundation for subsequent optimization and improvement.

摘要

儿童扁桃体手术后出血是一种严重且可能危及生命的并发症。本研究的目的是通过一项全国多中心回顾性研究,建立儿童扁桃体手术后出血的风险预警模型,为儿童扁桃体手术后的分级管理提供依据。对2022年1月15日至2023年5月15日来自不同省份15个研究中心的8854例接受全身麻醉下扁桃体切除术的儿童进行分层抽样。本研究的样本量为2724例,其中男性1096例,女性1628例。根据术后是否出血将儿童分为出血组和非出血组。采用随机森林算法构建风险预警模型。通过不断探索优化模型,提高了预测儿童扁桃体术后出血率的准确性,并通过十折交叉验证验证了模型的预测效果。在2724例儿童中,117例扁桃体切除术后出现术后出血,出血率为4.30%。将随机森林算法构建的训练集模型在测试集中进行验证,得到的预测准确率为98.72%,召回率为78.95%,ROC曲线下面积AUC为0.96。虽然随机森林模型的召回率有待提高,但整体准确率相当优异。它可以有效避免将阳性病例误判为阴性病例。它是一种可用于预测扁桃体术后出血率和临床医疗决策的有用工具,为后续的优化和改进奠定了良好的基础。