Xu Hongming, Qiu Shuyao, Wang Jinxia, Han Fugen, Xia Zhongfang, Ni Liyan, Ma Jing, Chen Chunguang, Gao Xingqiang, Zhang Junmei, Liu Haixia, Liu Haibing, Yao Hongbing, Zhuang Qianger, Song Wei, Zhao Sijun, Zhang Mingjun, Liu Dabo, Li Xiaoyan
Department of Otorhinolaryngology Head and Neck Surgery,Shanghai Children's Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai,200062,China.
Department of Pediatric Otorhinolaryngology,Shenzhen Hospital,Southern Medical University.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Oct;38(10):883-890. doi: 10.13201/j.issn.2096-7993.2024.10.001.
Hemorrhage after tonsil surgery in children is a serious and potentially life-threatening complication. The purpose of this study was to establish a risk warning model for hemorrhage after tonsil surgery in children through a national multi-center retrospective study, providing a basis for hierarchical management after tonsil surgery in children. Stratified sampling was performed on 8 854 children who underwent tonsillectomy under general anesthesia from 15 research centers in different provinces from January 15, 2022 to May 15, 2023. The sample size of this study was 2 724 cases, including 1 096 males and 1 628 females. Children were divided into bleeding and non-bleeding groups according to whether or not they had bleeding after surgery. The random forest algorithm was used to build a risk warning model. By continuously exploring the optimized model, the accuracy of predicting the postoperative bleeding rate of tonsils in children was improved, and the prediction effectiveness of the model was verified by ten-fold cross-validation. Among 2 724 children, 117 had postoperative bleeding after tonsillectomy, with a bleeding rate of 4.30%. The model constructed by the random forest algorithm for the training set was verified in the test set, and the obtained prediction accuracy was 98.72%, the recall rate was 78.95%, and the area under the ROC curve AUC was 0.96. Although the recall rate of the random forest model needs to be improved, the overall accuracy is quite excellent. It can effectively avoid misjudging positive cases as negative cases. It is a useful tool that can be used to predict the postoperative bleeding rate of tonsils and clinical medical decision-making, laying a good foundation for subsequent optimization and improvement.
儿童扁桃体手术后出血是一种严重且可能危及生命的并发症。本研究的目的是通过一项全国多中心回顾性研究,建立儿童扁桃体手术后出血的风险预警模型,为儿童扁桃体手术后的分级管理提供依据。对2022年1月15日至2023年5月15日来自不同省份15个研究中心的8854例接受全身麻醉下扁桃体切除术的儿童进行分层抽样。本研究的样本量为2724例,其中男性1096例,女性1628例。根据术后是否出血将儿童分为出血组和非出血组。采用随机森林算法构建风险预警模型。通过不断探索优化模型,提高了预测儿童扁桃体术后出血率的准确性,并通过十折交叉验证验证了模型的预测效果。在2724例儿童中,117例扁桃体切除术后出现术后出血,出血率为4.30%。将随机森林算法构建的训练集模型在测试集中进行验证,得到的预测准确率为98.72%,召回率为78.95%,ROC曲线下面积AUC为0.96。虽然随机森林模型的召回率有待提高,但整体准确率相当优异。它可以有效避免将阳性病例误判为阴性病例。它是一种可用于预测扁桃体术后出血率和临床医疗决策的有用工具,为后续的优化和改进奠定了良好的基础。