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中国深圳老年人群对肺炎球菌疫苗接种意愿增强:一项新冠疫情期间的横断面研究

Heightened Willingness toward Pneumococcal Vaccination in the Elderly Population in Shenzhen, China: A Cross-Sectional Study during the COVID-19 Pandemic.

作者信息

Zhang Minyi, Chen Hongbiao, Wu Fei, Li Qiushuang, Lin Qihui, Cao He, Zhou Xiaofeng, Gu Zihao, Chen Qing

机构信息

Department of Epidemiology, School of Public Health, Southern Medical University, Guangzhou 510515, China.

Department of Epidemiology and Infectious Disease Control, Longhua Centre for Disease Control and Prevention, Shenzhen 518109, China.

出版信息

Vaccines (Basel). 2021 Mar 3;9(3):212. doi: 10.3390/vaccines9030212.

Abstract

BACKGROUND

Elderly population is considered at high risk for pneumococcal diseases. The pneumococcal vaccine coverage presents extremely low among elderly people in China. However, the serious event of COVID-19 drives interest in the pneumococcal vaccine, prompting us investigating the willingness to accept the 23-valent pneumococcal polysaccharide vaccine (PPSV23) and influencing factors among people aged over 60 years during the COVID-19 pandemic.

METHODS

A cross-sectional study was employed using a self-administered questionnaire in Shenzhen City of China, elaborating the willingness toward PPSV23 in the elderly persons. Binomial logistic analyses were performed to estimate the influencing factors using odds ratios (ORs) and 95% confidence interval (CI).

RESULTS

Among 15,066 respondents, 91.5% presented a positive attitude toward PPSV23. Logistic analyses suggested the influencing factors included knowledge about pneumonia (adjusted OR [aOR] 1.391, 95%CI 1.214-1.593), perception of the seriousness of pneumonia (aOR 1.437, 95%CI 1.230-1.680) and preventing way for pneumonia (aOR 1.639, 95%CI 1.440-1.865), worried about getting pneumonia (aOR 2.751, 95%CI 2.444-3.096), understanding vaccine policy (aOR 1.774, 95%CI 1.514-2.079), and influenza vaccine (aOR 3.516 and 95%CI 2.261-5.468) and PPSV23 histories (aOR 3.199, 95%CI 1.492-6.860).

CONCLUSIONS

The interest surge in pneumococcal vaccine coincided with the COVID-19 outbreak, foreshadowing higher demand for pneumococcal vaccine in the near future.

摘要

背景

老年人群被认为是肺炎球菌疾病的高危人群。在中国老年人中,肺炎球菌疫苗接种率极低。然而,新冠疫情这一严重事件激发了人们对肺炎球菌疫苗的兴趣,促使我们调查在新冠疫情期间60岁以上人群接受23价肺炎球菌多糖疫苗(PPSV23)的意愿及影响因素。

方法

在中国深圳市采用自填式问卷进行横断面研究,阐述老年人对PPSV23的意愿。采用二项逻辑分析,使用比值比(OR)和95%置信区间(CI)估计影响因素。

结果

在15066名受访者中,91.5%对PPSV23持积极态度。逻辑分析表明,影响因素包括对肺炎的了解(调整后OR[aOR]1.391,95%CI 1.214 - 1.593)、对肺炎严重性的认知(aOR 1.437,95%CI 1.230 - 1.680)、肺炎预防方法(aOR 1.639,95%CI 1.440 - 1.865)、担心患肺炎(aOR 2.751,95%CI 2.444 - 3.096)、了解疫苗政策(aOR 1.774,95%CI 1.514 - 2.079)、流感疫苗接种史(aOR 3.516,95%CI 2.261 - 5.468)以及PPSV23接种史(aOR 3.199,95%CI 1.492 - 6.860)。

结论

肺炎球菌疫苗兴趣的激增与新冠疫情爆发同时出现,预示着在不久的将来对肺炎球菌疫苗的需求会更高。

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