Liu Shijun, Xu Erping, Liu Yan, Xu Yuyang, Wang Jun, Du Jian, Zhang Xiaoping, Che Xinren, Gu Wenwen
a Hangzhou Center for Disease Control and Prevention ; Hangzhou , China.
Hum Vaccin Immunother. 2014;10(10):2994-9. doi: 10.4161/21645515.2014.972155.
To investigate the coverage of the 23-valent pneumococcal polysaccharide vaccine (23-PPV) in the Chinese urban elderly population and to understand the attitudes, knowledge and beliefs of this population toward the 23-PPV vaccination.
A cross-sectional approach was employed to survey the willingness of this population to receive the 23-PPV vaccination. Two thousand 9 hundred 2 six subjects over the age of 60 y were enrolled via a multi-stage random sampling method from the urban community population in Hangzhou, China. The relationships between the variables and the willingness to receive the 23-PPV vaccination were computed as odds ratios (ORs) by multivariate analysis.
Of the participants, 21.77% were willing to undergo 23-PPV vaccination, and 61.65% of the subjects agreed that pneumonia is a serious disease among elderly people. The rate of reasonable perceptions about vaccination, including the perception about vaccine efficacy and safety, among the subjects was below 50%. Only 1.23% of subjects had been vaccinated with 23-PPV, and a similarly low rate was observed for the seasonal influenza vaccine (4.17%). The factors that were independently related to the willingness to receive the 23-PPV vaccine included consensus with the hazards of pneumonia (OR = 1.67, 95% CI: 1.28 - 2.17), the safety of vaccination (OR = 2.00, 95% CI: 1.54 - 2.59), advice about the 23-PPV vaccination from family members (OR = 2.37, 95% CI: 1.39 - 4.40), influenza vaccination history (OR = 2.57, 95% CI: 1.66 - 3.98) and pneumococcal vaccination history (OR = 7.48, 95% CI: 2.4-22.92).
The administration of the 23-PPV vaccine among the urban elderly population is not optimistic in China. Emphasis on persuasion from families and the improvement of knowledge about vaccination might encourage elderly people to get the 23-PPV vaccination. Suggestions from physicians did not affect the participants' willingness to get the 23-PPV vaccination in multivariate analysis, but elderly people typically visited the Community Health Center (CHC) in their residential districts, and thus, systematic encouragement from healthcare physicians might be the key to increasing 23-PPV vaccination.
调查23价肺炎球菌多糖疫苗(23-PPV)在中国城市老年人群中的覆盖情况,并了解该人群对23-PPV疫苗接种的态度、知识和观念。
采用横断面研究方法调查该人群接种23-PPV疫苗的意愿。通过多阶段随机抽样方法,从中国杭州城市社区人群中纳入2926名60岁以上的受试者。通过多变量分析计算变量与接种23-PPV疫苗意愿之间的关系,以比值比(OR)表示。
在参与者中,21.77%愿意接种23-PPV疫苗,61.65%的受试者认同肺炎在老年人中是一种严重疾病。受试者对疫苗接种的合理认知率,包括对疫苗有效性和安全性的认知,低于50%。仅1.23%的受试者接种过23-PPV疫苗,季节性流感疫苗的接种率同样较低(4.17%)。与接种23-PPV疫苗意愿独立相关的因素包括认同肺炎的危害性(OR = 1.67,95%CI:1.28 - 2.17)、疫苗接种安全性(OR = 2.00,95%CI:1.54 - 2.59)、家庭成员对23-PPV疫苗接种的建议(OR = 2.37,95%CI:1.39 - 4.40)、流感疫苗接种史(OR = 2.57,95%CI:1.66 - 3.98)和肺炎球菌疫苗接种史(OR = 7.48,95%CI:2.4 - 22.92)。
中国城市老年人群中23-PPV疫苗的接种情况不容乐观。强调家庭劝说以及提高疫苗接种知识水平可能会促使老年人接种23-PPV疫苗。在多变量分析中,医生的建议并未影响参与者接种23-PPV疫苗的意愿,但老年人通常会前往其居住小区的社区卫生服务中心(CHC),因此,医护人员的系统性鼓励可能是提高23-PPV疫苗接种率的关键。