子宫颈软斑病：一例报告

Malacoplakia of the Uterine Cervix: A Case Report.

作者信息

Saco Adela, Rakislova Natalia, Marimon Lorena, Torne Aureli, Diaz-Feijoo Berta, Salvador Rafael, Alos Silvia, Jordao Dercio, Hurtado Juan Carlos, Ordi Jaume

机构信息

Department of Pathology, Hospital Clinic, University of Barcelona, 08036 Barcelona, Spain.

Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), 08036 Barcelona, Spain.

出版信息

Pathogens. 2021 Mar 15;10(3):343. doi: 10.3390/pathogens10030343.

DOI:10.3390/pathogens10030343

PMID:33804212

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8000235/

Abstract

Malacoplakia is an uncommon chronic granulomatous inflammation that rarely affects the female genital tract. A case of a 78-year-old woman with malacoplakia involving the uterine cervix and the vagina is described. The patient complained of vaginal bleeding. Clinically, a 13-mm mass was detected in the cervix, which was confirmed by ultrasound scan and magnetic resonance imaging. Histological examination showed a dense histiocytic infiltrate with abundant Michaelis-Gutmann bodies involving the uterine cervix and the upper vagina. The presence of was confirmed in the lesion by immunohistochemistry and polymerase chain reaction. Only 12 cases of cervical malacoplakia have been reported to date. This condition should be included in the differential diagnosis of cervical tumors.

摘要

软斑病是一种罕见的慢性肉芽肿性炎症，很少累及女性生殖道。本文描述了一例78岁女性软斑病累及子宫颈和阴道的病例。患者主诉阴道出血。临床上，在宫颈发现一个13毫米的肿块，经超声扫描和磁共振成像证实。组织学检查显示子宫颈和阴道上段有密集的组织细胞浸润，并伴有大量Michaelis-Gutmann小体。通过免疫组织化学和聚合酶链反应在病变中证实了（此处原文缺失具体内容）的存在。迄今为止，仅报道了12例宫颈软斑病病例。这种情况应列入宫颈肿瘤的鉴别诊断中。