Malacoplakia of the uterine cervix: report of two cases.

Two cases of malacoplakia involving the uterine cervix are reported. Lesions of the genital tract caused by this uncommon granulomatous reaction may suggest malignancy clinically and may present with vaginal bleeding. Cytologic findings in cervical smears from both patients included inflammation and abundant histiocytes. The characteristic finding is the Michaelis-Gutmann body, which can be identified in cervical smears, especially with the use of PAS or von Kossa stain. Gram-negative bacilli may be cultured from the tissue or identified on Gram's stain. Antibiotics are probably effective in eradication, as is surgical excision.