Dehelean Liana, Romosan Ana Maria, Bucatos Bianca Oana, Papava Ion, Balint Rita, Bortun Ana Maria Cristina, Toma Mirela Marioara, Bungau Simona, Romosan Radu Stefan
Department of Neurosciences-Psychiatry, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Centre for Cognitive Research in Neuropsychiatric Pathology, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Healthcare (Basel). 2021 Mar 24;9(4):365. doi: 10.3390/healthcare9040365.
This study assesses the empathy level, cognitive performance and emotion recognition skills of remitted patients with schizophrenia, schizoaffective disorder and bipolar disorder, and also explores the relationship between impairments in the mentioned domains. The study was performed on 77 subjects divided into two groups: PAT sample (N = 37) included remitted patients with either schizophrenia, schizoaffective or bipolar disorder who were compared with healthy control subjects from the HC sample (N = 40). Along with sociodemographic and clinical data, empathy levels (using EQ (Empathy Quotient) scale), the ability to recognize another person's emotional state (using RMET (Reading the Mind in the Eyes Test)), and cognitive performance (using MoCA (Montreal Cognitive Assessment) Scale) were investigated. The intensity of the psychiatric symptoms was measured with BPRS-E (Brief Psychiatric Rating Scale-Expanded). The remitted patients had lower EQ ( = 0.02) and RMET ( < 0.0001) scores than the healthy subjects. In the PAT group, RMET scores were positively correlated with MoCA total scores. Both EQ and RMET scores were negatively correlated with BPRS-E total scores. Psychiatric disorder was a significant predictor for deficits in emotion recognition. There were no significant differences in RMET, EQ and MoCA scores between patients with respect to diagnosis, the type of antipsychotic or the associated medication. In both samples, females had higher empathy levels ( = 0.04) and better emotion recognition abilities ( = 0.04) than males. Patients with schizophrenia, schizoaffective or bipolar disorder, currently in remission, displayed lower empathy levels and poorer emotion recognition skills than healthy subjects. Poor emotion recognition skills were associated with symptom severity and impairments in global cognition.
本研究评估了精神分裂症、分裂情感性障碍和双相情感障碍缓解期患者的共情水平、认知表现和情绪识别能力，并探讨了上述领域功能损害之间的关系。该研究对77名受试者进行，分为两组：PAT样本（N = 37）包括精神分裂症、分裂情感性障碍或双相情感障碍的缓解期患者，与HC样本（N = 40）中的健康对照受试者进行比较。除社会人口统计学和临床数据外，还调查了共情水平（使用EQ（共情商数）量表）、识别他人情绪状态的能力（使用RMET（眼睛解读心智测试））和认知表现（使用MoCA（蒙特利尔认知评估）量表）。用BPRS-E（简明精神病评定量表扩展版）测量精神症状的强度。缓解期患者的EQ（ = 0.02）和RMET（ < 0.0001）得分低于健康受试者。在PAT组中，RMET得分与MoCA总分呈正相关。EQ和RMET得分均与BPRS-E总分呈负相关。精神障碍是情绪识别缺陷的重要预测因素。患者在RMET、EQ和MoCA得分方面，在诊断、抗精神病药物类型或相关药物方面没有显著差异。在两个样本中，女性的共情水平（ = 0.04）和情绪识别能力（ = 0.04）均高于男性。目前处于缓解期的精神分裂症、分裂情感性障碍或双相情感障碍患者，其共情水平低于健康受试者，情绪识别能力也较差。情绪识别能力差与症状严重程度和整体认知功能损害有关。
