• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

氟代芳基脲和酰胺的合成及其与胺的相互作用：开启荧光与有机自由基在智能鱼类新鲜度标签之路上的竞争。

Synthesis of Fluorogenic Arylureas and Amides and Their Interaction with Amines: A Competition between Turn-on Fluorescence and Organic Radicals on the Way to a Smart Label for Fish Freshness.

机构信息

Department of Chemistry, Faculty of Science, University of Burgos, 09001 Burgos, Spain.

出版信息

Molecules. 2021 Mar 5;26(5):1404. doi: 10.3390/molecules26051404.

DOI:10.3390/molecules26051404
PMID:33807775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7961427/
Abstract

We describe the synthesis of fluorogenic arylureas and amides and their interaction with primary or secondary amines under air and light in organic-aqueous mixtures to give rise to a new class of persistent organic radicals, described on the basis of their electron paramagnetic resonance (EPR), as well as UV-vis, fluorescence, NMR, and quantum mechanics calculations, and their prospective use as multi-signal reporters in a smart label for fish freshness.

摘要

我们描述了在空气和光存在下，在有机-水混合物中芳基脲和酰胺的荧光合成及其与伯胺或仲胺的相互作用，从而产生一类新的持久有机自由基。这些自由基是基于电子顺磁共振（EPR）以及紫外-可见、荧光、NMR 和量子力学计算来描述的，它们有望作为鱼类新鲜度智能标签中的多信号报告器。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/5abcc16c78c2/molecules-26-01404-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/1ae5b3597cb4/molecules-26-01404-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/1d4746ff58ae/molecules-26-01404-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/bcadfb3c598e/molecules-26-01404-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/614f7cde2918/molecules-26-01404-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/593d956a9d6c/molecules-26-01404-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/0fda5b6565a8/molecules-26-01404-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/67b11026d7f8/molecules-26-01404-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/f9fa4049d709/molecules-26-01404-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/aee6aac1232e/molecules-26-01404-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/5abcc16c78c2/molecules-26-01404-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/1ae5b3597cb4/molecules-26-01404-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/1d4746ff58ae/molecules-26-01404-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/bcadfb3c598e/molecules-26-01404-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/614f7cde2918/molecules-26-01404-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/593d956a9d6c/molecules-26-01404-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/0fda5b6565a8/molecules-26-01404-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/67b11026d7f8/molecules-26-01404-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/f9fa4049d709/molecules-26-01404-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/aee6aac1232e/molecules-26-01404-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd97/7961427/5abcc16c78c2/molecules-26-01404-g011.jpg

相似文献

1
Synthesis of Fluorogenic Arylureas and Amides and Their Interaction with Amines: A Competition between Turn-on Fluorescence and Organic Radicals on the Way to a Smart Label for Fish Freshness.氟代芳基脲和酰胺的合成及其与胺的相互作用：开启荧光与有机自由基在智能鱼类新鲜度标签之路上的竞争。
Molecules. 2021 Mar 5;26(5):1404. doi: 10.3390/molecules26051404.
2
Radical hydroxyalkylation of C-H bond adjacent to nitrogen of tertiary amides, ureas, and amines.叔酰胺、脲和胺中与氮相邻的C-H键的自由基羟烷基化反应。
J Am Chem Soc. 2005 Aug 24;127(33):11610-1. doi: 10.1021/ja053855q.
3
One-pot synthesis of amides from aldehydes and amines via C-H bond activation.一锅法通过 C-H 键活化从醛和胺合成酰胺。
Org Lett. 2012 Oct 5;14(19):5014-7. doi: 10.1021/ol302175v. Epub 2012 Sep 14.
4
A sensing label or gel loaded with an NIR emission fluorescence probe for ultra-fast detection of volatile amine and fish freshness.一种带有近红外发射荧光探针的传感标签或凝胶，用于快速检测挥发性胺和鱼类新鲜度。
Spectrochim Acta A Mol Biomol Spectrosc. 2024 Oct 5;318:124501. doi: 10.1016/j.saa.2024.124501. Epub 2024 May 22.
5
Perchlorotrityl radical-fluorophore conjugates as dual fluorescence and EPR probes for superoxide radical anion.高氯酸三苯甲基自由基-荧光团缀合物作为超氧阴离子自由基的双荧光和 EPR 探针。
Bioorg Med Chem. 2010 Jan 15;18(2):922-9. doi: 10.1016/j.bmc.2009.11.034. Epub 2009 Dec 4.
6
Heterogeneous Cu(II) -catalysed solvent-controlled selective N-arylation of cyclic amides and amines with bromo-iodoarenes.杂化 Cu(II) 催化溶剂控制的环状酰胺和胺与溴碘芳烃的选择性 N-芳基化反应。
Chemistry. 2013 Nov 11;19(46):15759-68. doi: 10.1002/chem.201302645. Epub 2013 Oct 2.
7
Catalytic acylation of amines with aldehydes or aldoximes.胺与醛或醛肟的催化酰化反应。
Org Lett. 2010 Nov 19;12(22):5096-9. doi: 10.1021/ol101978h. Epub 2010 Oct 14.
8
Preparation of beta- and gamma-lactams from carbamoyl radicals derived from oxime oxalate amides.由肟草酸酰胺衍生的氨基甲酰基自由基制备β-内酰胺和γ-内酰胺。
Org Biomol Chem. 2004 Mar 7;2(5):716-24. doi: 10.1039/b315223e. Epub 2004 Feb 3.
9
Nitroxides scavenge myeloperoxidase-catalyzed thiyl radicals in model systems and in cells.氮氧化物在模型系统和细胞中清除髓过氧化物酶催化的硫自由基。
J Am Chem Soc. 2004 Aug 4;126(30):9221-32. doi: 10.1021/ja0495157.
10
Switching from (R)- to (S)-selective chemoenzymatic DKR of amines involving sulfanyl radical-mediated racemization.从（R）-到（S）-选择性的酶促 DKR 胺涉及硫基自由基介导的外消旋化。
Org Biomol Chem. 2010 Sep 21;8(18):4165-8. doi: 10.1039/c0ob00054j. Epub 2010 Jul 27.

引用本文的文献

1
Synthesis of Catechol Derived Rosamine Dyes and Their Reactivity toward Biogenic Amines.儿茶酚衍生的若丹明染料的合成及其对生物胺的反应性。
Molecules. 2021 Aug 22;26(16):5082. doi: 10.3390/molecules26165082.

本文引用的文献

1
A Dual Fluorescence-Spin Label Probe for Visualization and Quantification of Target Molecules in Tissue by Multiplexed FLIM-EPR Spectroscopy.一种用于通过多重 FLIM-EPR 光谱法可视化和定量组织中靶分子的双荧光-自旋标记探针。
Angew Chem Int Ed Engl. 2021 Jun 25;60(27):14938-14944. doi: 10.1002/anie.202012852. Epub 2021 May 26.
2
A reaction-based sensing scheme for volatile organic amine reagents with the chromophoric-fluorogenic dual mode.基于反应的对挥发性有机胺试剂的具有生色-荧光双重模式的传感方案。
Spectrochim Acta A Mol Biomol Spectrosc. 2020 Oct 15;240:118539. doi: 10.1016/j.saa.2020.118539. Epub 2020 May 28.
3
Anion-π Complexes of Halides with p-Benzoquinones: Structures, Thermodynamics, and Criteria of Charge Transfer to Electron Transfer Transition.
卤化物与对苯醌的阴离子-π 配合物：结构、热力学和电子转移过渡电荷转移的判据。
J Am Chem Soc. 2019 Jun 12;141(23):9338-9348. doi: 10.1021/jacs.9b03277. Epub 2019 May 29.
4
Stable radical anions generated from a porous perylenediimide metal-organic framework for boosting near-infrared photothermal conversion.基于多孔苝二酰亚胺金属-有机框架生成的稳定自由基阴离子用于增强近红外光热转换。
Nat Commun. 2019 Feb 15;10(1):767. doi: 10.1038/s41467-019-08434-4.
5
Sensitive and rapid detection of aliphatic amines in water using self-stabilized micelles of fluorescent block copolymers.利用荧光嵌段共聚物的自稳定胶束灵敏快速检测水中的脂肪胺。
J Hazard Mater. 2019 Apr 15;368:630-637. doi: 10.1016/j.jhazmat.2019.01.097. Epub 2019 Jan 30.
6
Biogenic amines in foods.食品中的生物胺。
Food Sci Biotechnol. 2017 Dec 13;26(6):1463-1474. doi: 10.1007/s10068-017-0239-3. eCollection 2017.
7
Fingerprint Detection and Differentiation of Gas-phase Amines Using a Fluorescent Sensor Array Assembled from Asymmetric Perylene Diimides.基于不对称苝二酰亚胺荧光传感器阵列的气相伯胺指纹检测与区分
Sci Rep. 2018 Jul 6;8(1):10277. doi: 10.1038/s41598-018-28556-x.
8
Nanoscale Studies of Organic Radicals: Surface, Interface, and Spinterface.有机自由基的纳米尺度研究：表面、界面和范界面。
Acc Chem Res. 2018 Mar 20;51(3):753-760. doi: 10.1021/acs.accounts.7b00612. Epub 2018 Feb 21.
9
The Advantages of Cyclic Over Acyclic Carbenes To Access Isolable Capto-Dative C-Centered Radicals.环状卡宾相对于非环状卡宾在获取可分离的给体-受体型碳中心自由基方面的优势。
Chemistry. 2017 May 2;23(25):6206-6212. doi: 10.1002/chem.201700144. Epub 2017 Feb 13.
10
An air-persistent oxyallyl radical cation with simple di(methyl)amino substituents.一种具有简单二（甲基）氨基取代基的空气持久性氧烯丙基自由基阳离子。
Chem Commun (Camb). 2016 Sep 15;52(76):11422-11425. doi: 10.1039/c6cc06260a.