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光活化疗法前后接受牙齿修复治疗和牙周炎患者的微生物学特征——随机临床试验

Microbiologic Profiles of Patients with Dental Prosthetic Treatment and Periodontitis before and after Photoactivation Therapy-Randomized Clinical Trial.

作者信息

Mocanu Raluca Cristina, Martu Maria-Alexandra, Luchian Ionut, Sufaru Irina Georgeta, Maftei George Alexandru, Ioanid Nicoleta, Martu Silvia, Tatarciuc Monica

机构信息

Faculty of Dentistry, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Str., 700115 Iasi, Romania.

Department of Periodontology, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Str., 700115 Iasi, Romania.

出版信息

Microorganisms. 2021 Mar 30;9(4):713. doi: 10.3390/microorganisms9040713.

DOI:10.3390/microorganisms9040713
PMID:33808433
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8065635/
Abstract

Fixed prosthodontic dental restorations can potentially affect the periodontal tissues and vice versa, the periodontium can influence the longevity and esthetic appearance of dental restorations. We proposed an investigation on total bacterial load, specific periodontal pathogens, and periodontal clinical parameters in patients with dental fixed prosthesis and different degrees of periodontal tissue loss that followed photoactivation therapy (PDT) adjunctive to scaling and root planing. The study was conducted on 160 subjects, which were randomly assigned to scaling and root planing (SRP) alone (52 subjects, 256 sites), SRP and chlorhexidine rinsing (58 subjects, 276 sites), and SRP plus PDT (50 subjects, 318 sites). Periodontal parameters (plaque index, bleeding on probing, probing depth, and clinical attachment loss), followed by total bacterial load and specific periodontal pathogens ( and ) were examined in each patient at baseline, one and six months after. PDT exerted significant improvements both in clinical and microbiological load after one month, and these results were maintained 6 months after when compared to chlorhexidine rinsing or SRP alone, especially in severe periodontitis cases. Photoactivation therapy as an adjunctive periodontal therapeutic method was efficient in offering supplementary periodontal improvements in the clinical and microbiological parameters of patients with fixed dental prosthesis, particularly in severe periodontitis cases.

摘要

固定义齿修复可能会对牙周组织产生潜在影响,反之亦然,牙周组织也会影响牙齿修复体的使用寿命和美观。我们对接受光动力疗法(PDT)辅助龈上洁治和根面平整的不同程度牙周组织丧失的固定义齿修复患者的总细菌载量、特定牙周病原体和牙周临床参数进行了一项研究。该研究对160名受试者进行,他们被随机分为仅接受龈上洁治和根面平整(SRP)组(52名受试者,256个位点)、SRP加洗必泰冲洗组(58名受试者,276个位点)和SRP加PDT组(50名受试者,318个位点)。在基线、治疗后1个月和6个月时,对每位患者检查牙周参数(菌斑指数、探诊出血、探诊深度和临床附着丧失),随后检测总细菌载量和特定牙周病原体(和)。1个月后,PDT在临床和微生物负荷方面均有显著改善,与单独使用洗必泰冲洗或SRP相比,6个月后这些结果依然保持,尤其是在重度牙周炎病例中。光动力疗法作为一种辅助性牙周治疗方法,在改善固定义齿修复患者的临床和微生物学参数方面是有效的,特别是在重度牙周炎病例中。

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