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亚种（Guss.）Jalas 精油：对抗口腔病原体和口腔健康的盟友。

subsp. (Guss.) Jalas Essential Oil: An Ally against Oral Pathogens and Mouth Health.

机构信息

Department of Biology, University of Naples Federico II, 80126 Naples, Italy.

Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), Università degli Studi di Palermo, Viale delle Scienze, ed. 17, 90128 Palermo, Italy.

出版信息

Molecules. 2023 Jun 16;28(12):4803. doi: 10.3390/molecules28124803.

DOI:10.3390/molecules28124803
PMID:37375358
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10303722/
Abstract

The genus L., belonging to the Lamiaceae family, contains about 220 species with a distribution that mainly extends in Europe, northwest Africa, Ethiopia, Asia, and southern Greenland. Due to their excellent biological properties, fresh and/or dried leaves and aerial parts of several ssp. have been utilized in the traditional medicine of many countries. To evaluate not only the chemical aspects but also the biological properties, the essential oils (EOs), obtained from the pre-flowering and flowering aerial parts of subsp. (Guss.) Jalas, endemic to Marettimo Island (Sicily, Italy), were investigated. The chemical composition of the EOs, obtained by classical hydrodistillation and GC-MS and GC-FID analyses, showed the occurrence of similar amounts of monoterpene hydrocarbons, oxygenated monoterpenes, and sesquiterpene hydrocarbons. The main constituents of the pre-flowering oil were bisabolene (28.54%), -cymene (24.45%), and thymol methyl ether (15.90%). The EO obtained from the flowering aerial parts showed as principal metabolites bisabolene (17.91%), thymol (16.26%), and limonene (15.59%). The EO of the flowering aerial parts, and its main pure constituents, bisabolene, thymol, limonene, -cymene, and thymol methyl ether were investigated for their antimicrobial activity against oral pathogens and for their antibiofilm and antioxidant properties.

摘要

该属属于唇形科，约有 220 种，分布于欧洲、西北非、埃塞俄比亚、亚洲和格陵兰岛南部。由于其具有优良的生物特性，几种亚种的新鲜和/或干燥的叶子和地上部分已被许多国家的传统医学所利用。为了评估不仅是化学方面，而且是生物特性，从特有亚种的开花前和开花期的地上部分获得的精油（EO）。（Guss.）Jalas，位于西西里岛（意大利）的 Marettimo 岛，进行了调查。通过经典的水蒸馏和 GC-MS 和 GC-FID 分析获得的 EO 的化学成分表明，单萜烃、含氧单萜和倍半萜烃的含量相似。开花前油的主要成分是双醇（28.54%）、-柠檬烯（24.45%）和百里酚甲醚（15.90%）。开花期地上部分的精油显示主要代谢物为双醇（17.91%）、百里酚（16.26%）和柠檬烯（15.59%）。开花期地上部分的精油及其主要的纯成分，双醇、百里酚、柠檬烯、-柠檬烯和百里酚甲醚，被研究了其对口腔病原体的抗菌活性及其抗生物膜和抗氧化特性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/c50dcbca2ac6/molecules-28-04803-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/d3b01697b0f4/molecules-28-04803-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/e2b2e5073e8b/molecules-28-04803-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/383eced113a4/molecules-28-04803-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/a42787d4dd3a/molecules-28-04803-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/eaf239d912e5/molecules-28-04803-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/e87699cbfeb8/molecules-28-04803-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/bc3939bafdc8/molecules-28-04803-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/700681ca884a/molecules-28-04803-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/28ac734b6a44/molecules-28-04803-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/c50dcbca2ac6/molecules-28-04803-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/d3b01697b0f4/molecules-28-04803-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/e2b2e5073e8b/molecules-28-04803-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/383eced113a4/molecules-28-04803-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/a42787d4dd3a/molecules-28-04803-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/eaf239d912e5/molecules-28-04803-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/e87699cbfeb8/molecules-28-04803-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/bc3939bafdc8/molecules-28-04803-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/700681ca884a/molecules-28-04803-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/28ac734b6a44/molecules-28-04803-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/10303722/c50dcbca2ac6/molecules-28-04803-g010.jpg

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