Las Heras Etayo Nadia, Llamas Félix, Acedo Carmen
Biodiversity and Environment Management Department, Faculty of Biological and Environmental Sciences, University of León, 24007 León, Spain.
Plants (Basel). 2021 Mar 19;10(3):584. doi: 10.3390/plants10030584.
The species (L.) Fourr. has a large number of therapeutic uses reported in the traditional Spanish medicine. The growing interest in preserving the ethnopharmacological knowledge related to the botanical diversity existing in Spain and the interest in achieving scientific validation of the therapeutic properties of medicinal species has led to the development of this study. To do it, all the known medicinal uses of in Spain were compiled, then an exhaustive bibliographic research on its chemical composition was carried out, and finally, an in silico validation of the bioactive phytochemicals present in a higher proportion in the essential oil of : camphor, borneol, lucinone, glutinone, quercetin, kutdtriol, and kaempferol; in an attempt to justify the reported traditional uses of the species. It was found that much of the traditional medicinal uses of , along with the biological activity of its phytochemicals, are supported by scientific evidence. The results place this species in a prominent position to initiate possible lines of research to develop new, more effective drugs and improve therapies to treat conditions and diseases that affect the different organic systems of the human being.
物种（L.）Fourr. 在传统西班牙医学中有大量治疗用途的记载。人们对于保护与西班牙现存植物多样性相关的民族药理学知识的兴趣日益浓厚，同时也希望对药用植物的治疗特性进行科学验证，这促使了本研究的开展。为此，我们收集了该物种在西班牙所有已知的药用用途，接着对其化学成分进行了详尽的文献研究，最后，对该物种精油中含量较高的生物活性植物化学物质进行了计算机模拟验证，这些物质包括樟脑、冰片、卢西酮、谷胱甘肽、槲皮素、库特三醇和山奈酚，旨在为该物种所报道的传统用途提供依据。研究发现，该物种的许多传统药用用途及其植物化学物质的生物活性都有科学证据支持。这些结果使该物种处于突出地位，有望开启新的研究方向，以开发更有效新药并改进治疗方法，用于治疗影响人类不同有机系统 的病症和疾病。
