Sze G, Shin J, Krol G, Johnson C, Liu D, Deck M D
Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
Radiology. 1988 Jul;168(1):187-94. doi: 10.1148/radiology.168.1.3380956.
Prospective and retrospective studies of 75 patients were performed to assess the sensitivities of magnetic resonance (MR) imaging and computed tomography (CT) in the evaluation of suspected intraparenchymal brain metastases. The findings on MR images were equivalent to those on CT scans in 49 of the 75 patients; the remaining findings were discordant in 26 patients, and neither MR imaging nor CT was consistently superior. MR imaging demonstrated more metastases in nine of these 26 patients. However, contrast material-enhanced CT scans were superior in lesion depiction in eight of the 26 patients. Large enhanced lesions that were nearly isointense on MR images were seen well on CT scans. In several cases in which results were discordant, gadolinium-diethylenetriaminepentaacetic acid (DTPA)-enhanced MR images were obtained, and this agent behaved similarly to iodinated contrast agents. If indicated clinically, such as before surgery for a single metastasis, the authors perform both MR imaging and contrast-enhanced CT. Gd-DTPA-enhanced MR imaging may prove to be the method of choice for depiction of intraparenchymal metastases.
对75例患者进行了前瞻性和回顾性研究，以评估磁共振（MR）成像和计算机断层扫描（CT）在评估疑似脑实质内转移瘤方面的敏感性。75例患者中，有49例的MR图像表现与CT扫描结果相当；其余26例患者的检查结果不一致，MR成像和CT均未表现出持续的优势。在这26例患者中，有9例MR成像显示出更多的转移瘤。然而，在26例患者中，有8例对比剂增强CT扫描在病变显示方面更具优势。在MR图像上几乎等信号的大的强化病变在CT扫描上显示良好。在几例结果不一致的病例中，获取了钆喷酸葡胺（Gd-DTPA）增强的MR图像，该造影剂的表现与碘化造影剂相似。如果临床有指征，比如在对单个转移瘤进行手术前，作者会同时进行MR成像和对比增强CT检查。Gd-DTPA增强的MR成像可能被证明是显示脑实质内转移瘤的首选方法。
