Morato-Martínez Marina, Santurino Cristina, López-Plaza Bricia, Arcos-Castellanos Lucía, Clavero-Fraile Marta, Valero-Pérez Marlhyn, Palma Milla Samara, Valero Marlhyn, Gómez Candela Carmen
Clinical Nutrition and Dietetics Unit. Instituto de Investigación Sanitaria (IdiPAZ). Hospital Universitario La Paz.
Instituto de Investigación Sanitaria (IdiPAZ). Hospital Universitario La Paz.
Nutr Hosp. 2021 Jun 10;38(3):575-584. doi: 10.20960/nh.03409.
Introduction: breast cancer is the most common invasive cancer among women in developed countries. At diagnosis, approximately 70 % of women are overweight, and the additional weight gain that can result from the ensuing treatments has been associated with cancer recurrence and progression. Objectives: the main objective was to compare the effect of only a nutritional intervention (CG) with a nutrition education program (nutritional intervention, nutrition education, and physical activity) (IG) for 1 year. Methods: a total of 65 women with breast cancer who had been evaluated at the Clinical Nutrition Department, La Paz University Hospital, Madrid, Spain were recruited into 2 groups: a control group (CG) and an intervention group (IG). Results: the IG showed a significant reduction in body weight (-1.87 ± 3.41 vs. 1.48 ± 2.01 kg, p < 0.05), BMI (-0.61 ± 1.40 vs. 0.65 ± 0.88 kg/m2, p < 0.05), total cholesterol (-32.92 ± 38.45 vs. -3.23 ± 39.73 mg/dl, p < 0.05), and low-density lipoprotein cholesterol (-35.29 ± 27.50 vs. 6.33 ± 40.70 mg/dl, p < 0.05). Both groups were shown to be more conscious of the importance of physical activity, with increased consumption of grains, fruits, oily fish, and dairy. Conclusions: dietary interventions and physical activity were shown to be important to achieving several physical and physiological benefits that could reduce some risk factors associated with breast cancer recurrence and progression.
在发达国家，乳腺癌是女性中最常见的浸润性癌症。在确诊时，约70%的女性超重，而后续治疗可能导致的体重增加与癌症复发和进展有关。目的：主要目的是比较仅进行营养干预（对照组）与营养教育项目（营养干预、营养教育和体育活动）（干预组）为期1年的效果。方法：共招募了65名在西班牙马德里拉巴斯大学医院临床营养科接受评估的乳腺癌女性，分为2组：对照组（CG）和干预组（IG）。结果：干预组的体重显著降低（-1.87±3.41 vs. 1.48±2.01 kg，p<0.05）、体重指数（-0.61±1.40 vs. 0.65±0.88 kg/m²，p<0.05）、总胆固醇（-32.92±38.45 vs. -3.23±39.73 mg/dl，p<0.05）和低密度脂蛋白胆固醇（-35.29±27.50 vs. 6.33±40.70 mg/dl，p<0.05）。两组都表现出对体育活动重要性的更高认识，谷物、水果、油性鱼类和乳制品的摄入量增加。结论：饮食干预和体育活动对实现多种身体和生理益处很重要，这些益处可以降低一些与乳腺癌复发和进展相关的风险因素。
