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[癌症患者在迟发型超敏反应期间天然抗肿瘤抵抗力的激活]

[Activation of natural antitumor resistance in cancer patients during a delayed hypersensitivity reaction].

作者信息

Gordienko S M, Novichev A P, Avdiunicheva O E, Churilova L A

出版信息

Vopr Onkol. 1988;34(5):572-6.

PMID:3381499
Abstract

Factors influencing the effectiveness of BCG vaccine employed as part of complex therapy were studied in cases of lung and gastrointestinal cancer. The drug showed clinical effect and stimulated the effector function of monocytes, natural and antibody-dependent killers in tuberculin-positive patients only. The degree of stimulation was in correlation with that of delayed hypersensitivity reaction. A relationship between stimulation, increase in the level of effector-cells and intensification of cytolytic activity was established.

摘要

在肺癌和胃肠道癌病例中,研究了作为综合治疗一部分使用的卡介苗疫苗有效性的影响因素。该药物仅在结核菌素阳性患者中显示出临床效果,并刺激了单核细胞、自然杀伤细胞和抗体依赖性杀伤细胞的效应功能。刺激程度与迟发型超敏反应程度相关。建立了刺激、效应细胞水平增加与溶细胞活性增强之间的关系。

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