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新型精神药物贝米替尔在治疗虚弱症中的应用(临床药理学研究)

[Use of the new psychotropic preparation bemitil in treating asthenic disorders (clinico-pharmacological research)].

作者信息

Aleksandrovskiĭ Iu A, Bobkov Iu G, Neznamov G G, Serebriakova T V, Boĭko S S

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1988;88(3):109-15.

PMID:3381606
Abstract

In a series of 130 patients with asthenic conditions related to borderline forms of neuro-mental disturbances the authors compared clinico-pharmacological action of the actoprotector bemitil with that of nootropic drugs (piracetam and piridotol). The treatment with bemitil was either continuous or intermittent, being conducted according to the scheme elaborated in the course of the study. Bemitil proved to be more effective than piracetam and piriditol in relation to its influence on the manifestations of the asthenic symptom complex in general. Its application was characterized by a faster onset of the therapeutic effect and a peculiar mild psychostimulating action, primarily manifested in the impact on obligate manifestations of the asthenic disorders. The degree of the psychotropic action of the drug was found to be subject to changes depending on the scheme of its use.

摘要

在130例与边缘性神经精神障碍相关的虚弱状态患者中,作者比较了抗疲劳剂贝米替尔与益智药(吡拉西坦和匹立多醇)的临床药理作用。贝米替尔的治疗采用持续或间歇方式,按照研究过程中制定的方案进行。总体而言,贝米替尔在影响虚弱症状复合体表现方面比吡拉西坦和匹立多醇更有效。其应用的特点是治疗效果起效更快,具有独特的轻度精神兴奋作用,主要体现在对虚弱障碍的必然表现的影响上。发现该药物的精神作用程度会根据其使用方案而发生变化。

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