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一名患有上皮样胸膜间皮瘤(黏液样变体)的患者未经治疗却存活了很长时间。

A patient with epithelioid pleural mesothelioma (Myxoid variant) who survived for a long period without treatment.

作者信息

Mizuhashi Keiichi, Okamoto Kenzo, Kishimoto Takumi

机构信息

Center for Asbestos-Related Diseases, Toyama Rosai Hospital, Uozu-shi, Toyama, Japan.

Department of Pathology, Hokkaidoutyuuou Rosai Hospital, Iwamizawa-shi, Hokkaidou, Japan.

出版信息

Respir Med Case Rep. 2021 Mar 8;33:101381. doi: 10.1016/j.rmcr.2021.101381. eCollection 2021.

DOI:10.1016/j.rmcr.2021.101381
PMID:33816102
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8005851/
Abstract

Pleural mesothelioma is a disease with a very poor prognosis. Here, we report a mesothelioma patient who survived for 5 years and a half. As a result of the autopsy, the tumor was diagnosed as a myxoid variant, which is internationally proposed as a histological subtype of epithelioid mesothelioma with a relatively favorable prognosis. Since patients with this disease are expected to survive for a long period even without treatment, careful determination of the therapeutic approach is considered necessary. This report is considered to be the first of a myxoid variant epithelioid pleural mesothelioma in Japan.

摘要

胸膜间皮瘤是一种预后非常差的疾病。在此,我们报告一名存活了五年半的间皮瘤患者。尸检结果显示,该肿瘤被诊断为黏液样变体,国际上提议将其作为上皮样间皮瘤的一种组织学亚型,预后相对较好。由于即使未经治疗,这种疾病的患者也有望长期存活,因此认为有必要谨慎确定治疗方法。本报告被认为是日本首例黏液样变体上皮样胸膜间皮瘤病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/9fcb4f9695f6/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/76b0f188f11b/gr1a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/087d53d61d43/gr1b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/6a3822dafb46/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/196e14966bb2/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/0718a7d24a28/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/81970b6a442a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/fb368dde4c06/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/0141ecabe0ae/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/dff5931e4bda/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/9fcb4f9695f6/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/76b0f188f11b/gr1a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/087d53d61d43/gr1b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/6a3822dafb46/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/196e14966bb2/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/0718a7d24a28/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/81970b6a442a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/fb368dde4c06/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/0141ecabe0ae/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/dff5931e4bda/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fed/8005851/9fcb4f9695f6/gr9.jpg

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本文引用的文献

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Myxoid variant epithelioid pleural mesothelioma defines a favourable prognosis group: an analysis of 191 patients with pleural malignant mesothelioma.黏液样变型上皮样胸膜间皮瘤定义了一个预后良好的组群:191例胸膜恶性间皮瘤患者的分析
J Clin Pathol. 2017 Feb;70(2):179-182. doi: 10.1136/jclinpath-2016-203993. Epub 2016 Oct 18.
2
Malignant mesothelioma with a pronounced myxoid stroma: a clinical and pathological evaluation of 19 cases.具有显著黏液样基质的恶性间皮瘤:19例临床与病理评估
Virchows Arch. 2005 Nov;447(5):828-34. doi: 10.1007/s00428-005-0035-y. Epub 2005 Jul 14.
3
Computed tomographic findings of environmental asbestos-related malignant pleural mesothelioma.
环境性石棉相关恶性胸膜间皮瘤的计算机断层扫描结果
Respirology. 1998 Mar;3(1):33-8. doi: 10.1046/j.1440-1843.1998.00069.x.