一种来自恶性疟原虫的富含组氨酸的蛋白质及其与膜的相互作用。
A histidine-rich protein from Plasmodium falciparum and its interaction with membranes.
作者信息
Kilejian A, Jensen J B
出版信息
Bull World Health Organ. 1977;55(2-3):191-7.
Abstract
In previous studies, an unusual protein with 70% of histidine was isolated from Plasmodium lophurae. It was shown to have a possible function in the penetration of merozoites into erythrocytes. The results of the present study indicate the presence of a similar histidine-rich protein in Plasmodium falciparum. Like that of P. lophurae, the histidine-rich protein of P. falciparum is acid-soluble, but it has a slightly higher molecular weight.
摘要
在先前的研究中，从约氏疟原虫中分离出一种组氨酸含量达70%的异常蛋白质。已表明该蛋白质在裂殖子侵入红细胞过程中可能具有某种功能。本研究结果表明，恶性疟原虫中存在一种类似的富含组氨酸的蛋白质。与约氏疟原虫的情况一样，恶性疟原虫的富含组氨酸的蛋白质可溶于酸，但分子量略高。
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