PHCC, Primary Health Care Corporation, Doha, Qatar.
Interdisciplinary Laboratory in Neurosciences, Physiology and Psychology: Physical Activity, Health and Learning (LINP2), UFR STAPS, UPL, Paris Nanterre University, Nanterre, France.
Expert Rev Endocrinol Metab. 2021 May;16(3):147-153. doi: 10.1080/17446651.2021.1909472. Epub 2021 Apr 5.
: Changes in hematological parameters are becoming evident as important early markers of COVID-19. Type 2 Diabetes Mellitus (T2DM) has been shown to be associated with increased severity of COVID-19. In this study, we aim to explore the various hematological variables in COVID-19 positive patients with T2DM, so as to act early and improve patient outcomes.: Medical e-records of seventy adult patients with T2DM who were COVID-19 positive have been analyzed in this retrospective cohort study. Demographic, clinical and laboratory parameters for these patients were examined.: Of the seventy patients with T2DM, 48.88% had poorly controlled diabetes. 70.69% were pyrexial, 56.25% were tachycardic and 38.58% were asymptomatic on presentation. Amongst the hematological parameters, anemia was seen in 10% of males and 15.38% of females. 20% had a high red-blood-cell-distribution-width (RDW). 7.27% had thrombocytosis and 3.64% had thrombocytopenia. 73.3% had a high platelet-distribution-width (PDW) and 44.44% had an increased mean-platelet-volume (MPV). 16.36% were neutropenic and 16.67% had lymphocytopenia.: Diabetic COVID-19 positive patients have been shown to have prominent manifestations of the hemopoietic-system with varied hematological profiles. Recognizing the implications of these variables early in primary-care, can help clinicians aid management decisions and dictate early referral to secondary-care services, to help improve prognosis.
: 血液学参数的变化正在成为 COVID-19 的重要早期标志物。2 型糖尿病(T2DM)已被证明与 COVID-19 的严重程度增加有关。在这项研究中,我们旨在探讨 COVID-19 阳性 T2DM 患者的各种血液学变量,以便及早采取行动,改善患者的预后。: 在这项回顾性队列研究中,分析了 70 例 T2DM 合并 COVID-19 阳性成年患者的医疗电子记录。检查了这些患者的人口统计学、临床和实验室参数。: 在 70 例 T2DM 患者中,48.88%的患者糖尿病控制不佳。70.69%的患者发热,56.25%的患者心动过速,38.58%的患者无症状。在血液学参数中,10%的男性和 15.38%的女性出现贫血。20%的患者红细胞分布宽度(RDW)升高。7.27%的患者血小板增多,3.64%的患者血小板减少。73.3%的患者血小板分布宽度(PDW)升高,44.44%的患者平均血小板体积(MPV)升高。16.36%的患者中性粒细胞减少,16.67%的患者淋巴细胞减少。: COVID-19 阳性的糖尿病患者表现出明显的造血系统表现,具有不同的血液学特征。在初级保健中及早认识到这些变量的意义,可以帮助临床医生做出管理决策,并决定早期转介到二级保健服务,以帮助改善预后。