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血小板分布宽度在轻症 COVID-19 患者中的诊断价值。

The diagnostic value of platelet distribution width in patients with mild COVID-19.

机构信息

Department of Critical Care Medicine, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.

Department of General Surgery, The Third People's Hospital of Dalian, Dalian, China.

出版信息

J Clin Lab Anal. 2021 Apr;35(4):e23703. doi: 10.1002/jcla.23703. Epub 2021 Mar 27.

Abstract

COVID-19 has a worldwide distribution; however, there is no effective diagnosis marker, especially for the mild-type COVID-19. The purpose of the current study was to identify parameters for mild-type COVID-19. We retrospectively analyzed a single-center data of patients with mild COVID-19. Forty patients diagnosed with COVID-19 were enrolled. Peripheral blood indices between the admission and discharge times were collected and analyzed. The platelet distribution width (PDW) was shown to be an indicator of significant change. The receiver operating characteristic curve for PDW was 0.7; the sensitivity and specificity for PDW were 82.5% and 55.0%, respectively. Therefore, a potential diagnostic value of PDW for mild-type COVID-19 was demonstrated.

摘要

COVID-19 分布于全球各地;然而,目前仍缺乏有效的诊断标志物,尤其是对于轻症 COVID-19 患者。本研究旨在寻找轻症 COVID-19 的诊断参数。我们回顾性分析了单一中心轻症 COVID-19 患者的数据。共纳入 40 例确诊为 COVID-19 的患者。收集并分析其入院和出院时的外周血指标。血小板分布宽度(PDW)显示为显著变化的指标。PDW 的受试者工作特征曲线为 0.7;PDW 的灵敏度和特异性分别为 82.5%和 55.0%。因此,PDW 对轻症 COVID-19 具有潜在的诊断价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0a9/8059752/145bc1a3276a/JCLA-35-e23703-g001.jpg

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