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计时起立行走测试(TUG)参考值及对新加坡社区居住成年人跌倒风险和失能的预测界值:义顺横断面研究和新加坡老龄化纵向研究。

Timed Up and Go (TUG) Reference Values and Predictive Cutoffs for Fall Risk and Disability in Singaporean Community-Dwelling Adults: Yishun Cross-Sectional Study and Singapore Longitudinal Aging Study.

机构信息

Faculty of Health and Social Sciences, Singapore Institute of Technology, Singapore; School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, United Kingdom.

Geriatric Education and Research Institute, Singapore.

出版信息

J Am Med Dir Assoc. 2021 Aug;22(8):1640-1645. doi: 10.1016/j.jamda.2021.03.002. Epub 2021 Apr 2.

Abstract

OBJECTIVES

The "timed up and go" (TUG) test is a simple and widely used test of overall functional mobility. There is a paucity of TUG normative data among Asian individuals who differ in habitual gait speed and fall risk from Western population. The objectives of this study were to determine TUG reference values and optimum cutoffs predicting prevalent and incident disability for community-dwelling adults.

DESIGN

One cross-sectional (Study 1-Yishun Study) and one longitudinal (Study 2-Singapore Longitudinal Aging Study) study in Singapore.

SETTING AND PARTICIPANTS

Study 1 comprised 538 nondisabled, community-dwelling adults aged between 21 and 90 years. Study 2 comprised 1356 community-dwelling older adults aged ≥55 years followed for 3 years.

METHODS

Study 1 collected TUG reference values and assessed physiological fall risk (PFR) using the Physiological Profile Assessment (PPA). Study 2 assessed association of TUG with disability with the Barthel Index and the Lawton scale at baseline and follow-up.

RESULTS

From Study 1, mean TUG time for individuals aged 60 to 74 years was 9.80 seconds, shorter than values reported for Westerners of 12.30 seconds. It was significantly associated with high PFR [odds ratio (OR) 1.14, 95% confidence interval (CI) 1.03-1.27], 74.0% agreement, Cohen's kappa = 0.314 (95% CI 0.238-0.390); area under the curve = 0.85 (95% CI 0.80-0.90). A TUG cutoff of 10.2 seconds discriminated high PFR from low PFR with 84.4% sensitivity and 72.6% specificity. In Study 2, the threshold for observing significantly increased risk of disability was ≥9.45 seconds for prevalent disability (OR 2.98, 95% CI 1.41-6.78), functional decline (OR 2.68, 95% CI 1.33-5.80), and incidental disability (OR 2.25, 95% CI 1.08-4.97).

CONCLUSIONS AND IMPLICATIONS

TUG reference values and cutoff predicting disability for community-dwelling older adults in Singapore are consistent with Asian data and lower than for Western individuals. TUG could be used to guide development and evaluation of risk screening of adverse health outcomes across the life span in Singapore.

摘要

目的

“计时起立行走”(TUG)测试是一种简单且广泛应用于整体功能移动性的测试。亚洲人与西方人群的习惯步态速度和跌倒风险不同,因此 TUG 参考数据很少。本研究的目的是确定 TUG 的参考值和最佳截断值,以预测社区居住成年人的普遍和新发残疾。

设计

一项在新加坡进行的横断面(研究 1-义顺研究)和一项纵向(研究 2-新加坡老龄化纵向研究)研究。

地点和参与者

研究 1 纳入了 538 名无残疾的社区居住成年人,年龄在 21 至 90 岁之间。研究 2 纳入了 1356 名年龄≥55 岁的社区居住老年人,随访 3 年。

方法

研究 1 收集了 TUG 的参考值,并使用生理概况评估(PPA)评估了生理跌倒风险(PFR)。研究 2 在基线和随访时使用巴氏量表和劳顿量表评估了 TUG 与残疾的相关性。

结果

来自研究 1 的结果显示,60 至 74 岁人群的 TUG 时间平均值为 9.80 秒,短于西方人 12.30 秒的报告值。它与高 PFR 显著相关[比值比(OR)1.14,95%置信区间(CI)1.03-1.27],一致性为 74.0%,Cohen's kappa 值为 0.314(95%CI 0.238-0.390);曲线下面积为 0.85(95%CI 0.80-0.90)。TUG 截断值为 10.2 秒可区分高 PFR 和低 PFR,敏感性为 84.4%,特异性为 72.6%。在研究 2 中,观察到残疾的风险显著增加的阈值为≥9.45 秒,用于普遍残疾(OR 2.98,95%CI 1.41-6.78)、功能下降(OR 2.68,95%CI 1.33-5.80)和偶发性残疾(OR 2.25,95%CI 1.08-4.97)。

结论和意义

新加坡社区居住老年人的 TUG 参考值和预测残疾的截断值与亚洲数据一致,且低于西方人群。TUG 可用于指导新加坡全生命周期不良健康结果风险筛查的制定和评估。

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