From the Kessler Institute for Rehabilitation, West Orange, New Jersey (SCK, BP, RD, BMG); Rutgers NJ Medical School, Newark, New Jersey (SCK, FE, BP, BMG); Kessler Foundation, West Orange, New Jersey (SCK, FE, BMG); and Select Medical Corporation, Mechanicsburg, Pennsylvania (SCK, GD, BP, SH, BMG).
Am J Phys Med Rehabil. 2021 May 1;100(5):419-423. doi: 10.1097/PHM.0000000000001729.
The aim of the study was to determine the prevalence of deep venous thrombosis detected by duplex screening and risk factors associated with deep venous thrombosis in patients with COVID-19 upon admission to an inpatient rehabilitation hospital.
This is a retrospective review.
The setting is three freestanding inpatient rehabilitation hospitals operating as one system.
The participants are consecutive patients with a diagnosis of COVID-19 admitted to an inpatient rehabilitation hospital without a diagnosis of deep venous thrombosis or screening duplex ultrasound prior to transfer.
A duplex ultrasound of lower limbs was performed upon admission to inpatient rehabilitation hospital.
Primary outcome was the percentage of admission patients with a lower limb deep venous thrombosis. Secondary factors included potential risk factors for a positive screen for deep venous thrombosis.
A lower limb deep venous thrombosis was diagnosed in 22% (25/113) of the patients tested, with eight patients (7.1%) having a proximal deep venous thrombosis. Risk factors for screening positive for a deep venous thrombosis included being male, younger, and having been on a ventilator during the acute illness.
The high rate of deep venous thrombosis observed in these patients suggests that the risk of venous thromboembolic disorders after severe COVID-19 illness is considerable and surveillance measures of such patients should be undertaken.
本研究旨在确定在收治到住院康复医院的 COVID-19 患者中，通过双功能超声筛查发现的深静脉血栓形成的患病率，以及与深静脉血栓形成相关的危险因素。
这是一项回顾性研究。
三个独立的住院康复医院作为一个系统运作。
连续患有 COVID-19 诊断的患者，在转入前没有深静脉血栓形成或双功能超声筛查的诊断。
在收治到住院康复医院时进行下肢双功能超声检查。
主要结局是下肢深静脉血栓形成的入院患者比例。次要因素包括深静脉血栓形成阳性筛查的潜在危险因素。
在接受测试的 113 名患者中，22%（25/113）诊断出下肢深静脉血栓形成，8 名患者（7.1%）存在近端深静脉血栓形成。深静脉血栓形成筛查阳性的危险因素包括男性、年轻和急性疾病期间使用呼吸机。
这些患者中观察到的深静脉血栓形成率较高表明，严重 COVID-19 疾病后静脉血栓栓塞疾病的风险相当大，应对这些患者进行监测措施。
