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应用吲哚菁绿荧光血管造影增强结直肠吻合口安全性:更新。

Enhancing colorectal anastomotic safety with indocyanine green fluorescence angiography: An update.

机构信息

Department of Surgery and Interventional Sciences, University College London, University College London Hospitals, London, UK.

Department of Surgery and Interventional Sciences, University College London, University College London Hospitals, London, UK.

出版信息

Surg Oncol. 2022 Aug;43:101545. doi: 10.1016/j.suronc.2021.101545. Epub 2021 Mar 19.

Abstract

Reducing anastomotic leak (AL) continues to be a main focus in colorectal research. Several new technologies have been developed with an aim to reduce this fluorescence angiography (FA) with indocyanine green (ICG) in colorectal surgery is now a well-established technique. By using FA we are able to have a visual representation of perfusion which aids intraoperative decision making. The main impact is change in the level of bowel transection at the proximal side of an anastomosis. Previous studies have shown that routine FA use is safe and reproducible. Recent results from randomized control trials and meta-analyses show that FA use reduces the rate of anastomotic leak. The main limitation of FA is its lack of ability to quantify perfusion. Novel technologies are being developed that will quantify tissue perfusion and oxygenation. Overall, FA is a safe technique and we would advocate its routine use.

摘要

降低吻合口漏(AL)仍然是结直肠研究的主要焦点。已经开发了几种新技术,目的是减少这种荧光血管造影(FA)在结直肠手术中,吲哚菁绿(ICG)现在是一种成熟的技术。通过使用 FA,我们能够对灌注进行可视化,从而辅助术中决策。主要影响是改变吻合近端肠段的切割水平。先前的研究表明,常规 FA 的使用是安全且可重复的。最近的随机对照试验和荟萃分析结果表明,FA 的使用降低了吻合口漏的发生率。FA 的主要局限性在于其缺乏量化灌注的能力。正在开发新的技术来量化组织灌注和氧合。总的来说,FA 是一种安全的技术,我们主张常规使用。

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