The Ethics of Deliberate Exposure to SARS-CoV-2 to Induce Immunity.

We explore the ethics of deliberately exposing consenting adults to SARS-CoV-2 to induce immunity to the virus ('DEI' for short). We explain what a responsible DEI program might look like. We explore a consequentialist argument for DEI according to which DEI is a viable harm-reduction strategy. Then we consider a nonconsequentialist argument for DEI that draws on the moral significance of consent. Additionally, we consider arguments for the view that DEI is unethical on the grounds that, given that large-scale DEI would be highly likely to result in some severe illnesses and deaths, DEI amounts to a form of killing. Our thesis is that incorporating a DEI program alongside the status quo 'calibrate the curve' responses could have significant advantages at the early stages of pandemics. These potential advantages mean that, at a minimum, research into DEI would have been justified early in the COVID-19 pandemic and that DEI programs should be explored as potential additions to our overall approach to emerging pandemics in the future.