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转移性骨肿瘤的骨科局部治疗

[Orthopedic local treatment of metastatic bone tumor].

作者信息

Usui M, Ishii S, Matsuyama T, Asano S, Fujisaki T, Ishikawa I, Kosakai Y

机构信息

Dept. of Orthopedic Surgery, Sapporo Medical College.

出版信息

Gan To Kagaku Ryoho. 1988 Apr;15(4 Pt 2-2):1365-9.

PMID:3382205
Abstract

Since 1971, we have treated 76 patients with metastatic bone tumor. Forty-eight of 76 cases were treated surgically. In 34 cases, removal of metastatic foci of the spine was attempted from the anterior and/or posterior approach. In the remaining 14 cases, resection of the tumor with or without prosthetic replacement, osteosynthesis, or amputation was performed according to the site of bone metastasis. In cases of spinal metastasis, if foci were located anteriorly, resection and replacement of vertebral body by ceramic spacer and/or bone cement was effective for both relief of pain and reduction of paralysis. If foci were located posteriorly, however, the results of simple laminectomy were poor, and those of spinal instrumentation in addition to laminectomy were satisfactory. In the treatment of metastatic foci of pelvis, scapula and long bone, the results of orthopedic surgery were satisfactory, because relief of pain and maintenance of function were achieved in almost all cases. From the standpoint of prolongation of life, 15 out of 76 cases (20%) were alive with or without disease; 13 of them were treated not only surgically but also by radiation and/or chemotherapy.

摘要

自1971年以来,我们共治疗了76例转移性骨肿瘤患者。76例中有48例接受了手术治疗。其中34例尝试从前路和/或后路切除脊柱转移灶。其余14例则根据骨转移部位进行肿瘤切除,术中或植入假体、或进行骨固定、或实施截肢。对于脊柱转移病例,如果转移灶位于前方,采用陶瓷间隔物和/或骨水泥切除并置换椎体,对于缓解疼痛和减轻瘫痪均有效。然而,如果转移灶位于后方,单纯椎板切除术效果不佳,而在椎板切除术基础上进行脊柱内固定术的效果令人满意。在治疗骨盆、肩胛骨和长骨转移灶时,矫形外科手术效果令人满意,因为几乎所有病例均实现了疼痛缓解和功能维持。从延长生命的角度来看,76例中有15例(20%)存活,无论是否伴有疾病;其中13例不仅接受了手术治疗,还接受了放疗和/或化疗。

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