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类风湿关节炎、骨关节炎和反应性关节炎患者血清及滑液中腺苷脱氨酶活性

Serum and synovial fluid adenosine deaminase activity in patients with rheumatoid arthritis, osteoarthritis, and reactive arthritis.

作者信息

Yuksel H, Akoğlu T F

机构信息

Department of Medicine, Marmara University Medical School, Istanbul, Turkey.

出版信息

Ann Rheum Dis. 1988 Jun;47(6):492-5. doi: 10.1136/ard.47.6.492.

DOI:10.1136/ard.47.6.492
PMID:3382270
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1003552/
Abstract

Adenosine deaminase activity was determined in paired samples of serum and synovial fluid taken from patients with rheumatoid arthritis (n = 12), reactive arthritis (n = 13), and osteoarthritis (n = 7), and the value of this investigation in the diagnosis of synovial swellings was assessed. Increased activity was found in the synovial fluid taken from patients with rheumatoid disease and reactive arthritis, though values were less raised in the latter. Synovial fluid taken from patients with osteoarthritis did not show significantly raised adenosine deaminase activity as compared with that of normal controls (n = 3).

摘要

对类风湿性关节炎患者(n = 12)、反应性关节炎患者(n = 13)和骨关节炎患者(n = 7)的配对血清和滑液样本进行了腺苷脱氨酶活性测定,并评估了该检查在滑膜肿胀诊断中的价值。类风湿性疾病和反应性关节炎患者的滑液中发现活性增加,不过后者的值升高程度较小。与正常对照组(n = 3)相比,骨关节炎患者的滑液中腺苷脱氨酶活性未显示出明显升高。

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