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采用肌瓣旋转术治疗婴幼儿术后纵隔炎

Management of postoperative mediastinitis in infants and children by muscle flap rotation.

作者信息

Stiegel R M, Beasley M E, Sink J D, Hester T R, Guyton R A, Perrella A M, Williams W H

机构信息

Department of Surgery, Emory University School of Medicine, Atlanta, GA.

出版信息

Ann Thorac Surg. 1988 Jul;46(1):45-6. doi: 10.1016/s0003-4975(10)65850-x.

Abstract

Between July 1, 1976, and June 30, 1986, at the Henrietta Egleston Hospital for Children, 2,242 infants and children underwent palliation or repair of a congenital heart defect. Twenty-one (0.94%) of these patients developed mediastinitis following a median sternotomy. Nineteen of these twenty-one patients had required cardiopulmonary bypass. All patients had positive mediastinal cultures. The first 8 patients were managed traditionally by debridement and irrigation. Three of these patients suffered serious metabolic complications related to the povidone-iodine irrigant, which resulted in 1 death. Another patient died from persistent sepsis following debridement. Subsequently, 13 patients were managed by early debridement and rotation of the pectoralis major or rectus abdominis muscle flaps, or both. Following muscle flap rotation and early wound closure, 2 patients had subsequent incisional complications. One patient had incisional dehiscence and 1 had a superficial skin separation. Two deaths in this group, 28 and 51 days, respectively, following muscle flap rotation, resulted from nonincisional problems in patients with healed median sternotomies. The group having muscle flap rotation required a significantly shorter duration of postoperative ventilatory support (3.2 versus 24 days, p less than 0.05) and a significantly shorter confinement in the intensive care unit (6.2 versus 33 days, p less than 0.01). Also, the physiological and physical trauma of continued wound care in the awake child was minimized in the group with muscle flap rotation.

摘要

1976年7月1日至1986年6月30日期间,在亨丽埃塔·埃格尔斯顿儿童医院,2242名婴幼儿和儿童接受了先天性心脏缺陷的姑息治疗或修复手术。其中21名(0.94%)患者在正中胸骨切开术后发生了纵隔炎。这21名患者中有19名需要进行体外循环。所有患者的纵隔培养结果均为阳性。最初的8名患者采用传统的清创和冲洗方法进行治疗。其中3名患者出现了与聚维酮碘冲洗液相关的严重代谢并发症,导致1例死亡。另1名患者在清创后死于持续性败血症。随后,13名患者采用早期清创并转移胸大肌或腹直肌肌瓣,或两者同时转移的方法进行治疗。在肌瓣转移和早期伤口闭合后,2名患者出现了后续的切口并发症。1名患者切口裂开,1名患者出现浅表皮肤分离。该组中有2名患者分别在肌瓣转移后28天和51天死亡,死亡原因是正中胸骨切开术伤口已愈合的患者出现了非切口问题。采用肌瓣转移的患者术后通气支持时间明显缩短(3.2天对24天,p<0.05),在重症监护病房的住院时间也明显缩短(6.2天对33天,p<0.01)。此外,在清醒儿童中,肌瓣转移组持续伤口护理的生理和身体创伤降至最低。

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