Du Xing, She Yuxiao, Ou Yunsheng, Zhu Yong, Luo Wei, Jiang Dianming
Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, China.
Biomed Res Int. 2021 Mar 20;2021:6693446. doi: 10.1155/2021/6693446. eCollection 2021.
To compare the efficacy of oblique lateral interbody fusion (OLIF) and transforaminal lumbar interbody fusion (TLIF) in single-level degenerative lumbar spondylolisthesis (DLS).
A retrospective analysis of patients who underwent single-level DLS surgery in our department from 2015 to 2018 was performed. According to the surgical method, the enrolled patients were divided into two groups, namely, the OLIF group who underwent OLIF combined with percutaneous pedicle screw fixation (PPSF) and the TLIF group. Clinical outcomes included operation time, operation blood loss, postoperative drainage, hospital stay, visual analog scale (VAS) score, Oswestry disability index (ODI), and complications, and imaging outcomes included upper vertebral slip, intervertebral space height (ISH), intervertebral foramen height (IFH), intervertebral space angle (ISA), lumbar lordosis (LL), and bone fusion rate. All outcomes were recorded and analyzed.
A total of 65 patients were finally included, and there were 28 patients and 37 patients in the OLIF group and the TLIF group, respectively. The OLIF group showed shorter operation time, less blood loss, less postoperative drainage, and shorter hospital stay than the TLIF group ( < 0.05). The ISH, IFH, ISA, and LL were all larger in the OLIF group at postoperative and last follow-up ( < 0.05), but the degree of upper vertebral slip was found no difference between the two groups ( > 0.05). The bone graft fusion rate of OLIF group and TLIF group at 3 months, 6 months, and last follow-up was 78.57%, 92.86%, and 100% and 70.27%, 86.49%, and 97.30%, respectively, and no significant differences were found ( > 0.05). Compared with the TLIF group, the OLIF group showed a superior improvement in VAS and ODI at 1 month, 3 months, and 6 months postoperative ( < 0.05), but no differences were found at 12 months postoperative and the last follow-up ( > 0.05). There was no significant difference in complications between the two groups, with 4 patients and 6 patients in the OLIF group and TLIF group, respectively ( > 0.05).
Compared with TLIF, OLIF showed the advantages of less surgical invasion, better decompression effect, and faster postoperative recovery in single-level DLS surgery.
比较斜外侧椎间融合术(OLIF)与经椎间孔腰椎椎间融合术(TLIF)治疗单节段退变性腰椎滑脱症(DLS)的疗效。
对2015年至2018年在我科接受单节段DLS手术的患者进行回顾性分析。根据手术方式,将纳入患者分为两组,即接受OLIF联合经皮椎弓根螺钉内固定(PPSF)的OLIF组和TLIF组。临床结果包括手术时间、术中出血量、术后引流量、住院时间、视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)及并发症,影像学结果包括上位椎体滑移、椎间隙高度(ISH)、椎间孔高度(IFH)、椎间隙角(ISA)、腰椎前凸(LL)及骨融合率。记录并分析所有结果。
最终纳入65例患者,OLIF组28例,TLIF组37例。OLIF组手术时间短、出血量少、术后引流量少、住院时间短,与TLIF组比较差异有统计学意义(P<0.05)。术后及末次随访时,OLIF组的ISH、IFH、ISA及LL均大于TLIF组(P<0.05),但两组上位椎体滑移程度差异无统计学意义(P>0.05)。OLIF组与TLIF组在术后3个月、6个月及末次随访时的植骨融合率分别为78.57%、92.86%、100%及70.27%、86.49%、97.30%,差异无统计学意义(P>0.05)。与TLIF组比较,OLIF组术后1个月、3个月及6个月时VAS及ODI改善更明显(P<0.05),但术后12个月及末次随访时差异无统计学意义(P>0.05)。两组并发症发生率差异无统计学意义,OLIF组4例,TLIF组6例(P>0.05)。
在单节段DLS手术中,与TLIF相比,OLIF具有手术创伤小、减压效果好、术后恢复快等优点。