舒必利对大鼠盐诱导利尿的抑制作用。
Inhibition of saline-induced diuresis in the rat by sulpiride.
作者信息
Imondi A R, Hagerman L M, Belair E J
出版信息
Experientia. 1979 Feb 15;35(2):251-2. doi: 10.1007/BF01920647.
PMID:33825
Abstract
Sulpiride (120 mg/kg, i.p.) inhibited saline-induced diuresis in the rat, an effect not observed with haloperidol, clozapine, pimozide or chloromazine. The antidiuretic effect of sulpiride also occurred in hypophysectomized rats suggesting that the response was not prolactin-mediated.
摘要
舒必利（120毫克/千克，腹腔注射）可抑制大鼠生理盐水诱导的利尿作用，而氟哌啶醇、氯氮平、匹莫齐特或氯丙嗪则未观察到这种作用。舒必利的抗利尿作用在垂体切除的大鼠中也会出现，这表明该反应不是由催乳素介导的。
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