The Sterile Services Decontamination Unit, Wrightington, Wigan and Leigh Teaching Hospitals NHS Foundation Trust, National Health Service, Bolton BL6 4SB, U.K.
School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, U.K.
Emerg Top Life Sci. 2021 May 14;5(1):169-176. doi: 10.1042/ETLS20200333.
Nanotechnology has received considerable attention and interest over the past few decades in the field of biomedicine due to the wide range of applications it provides in disease diagnosis, drug design and delivery, biomolecules detection, tissue engineering and regenerative medicine. Ultra-small size and large surface area of nanomaterials prove to be greatly advantageous for their biomedical applications. Moreover, the physico-chemical and thus, the biological properties of nanomaterials can be manipulated depending on the application. However, stability, efficacy and toxicity of nanoparticles remain challenge for researchers working in this area. This mini-review highlights the recent advances of various types of nanoparticles in biomedicine and will be of great value to researchers in the field of materials science, chemistry, biology and medicine.
在过去的几十年中，纳米技术因其在疾病诊断、药物设计和输送、生物分子检测、组织工程和再生医学等方面的广泛应用，在生物医药领域受到了相当大的关注和兴趣。纳米材料的超小尺寸和大表面积证明对其生物医药应用非常有利。此外，纳米材料的物理化学性质，从而其生物性质可以根据应用进行操纵。然而，纳米粒子的稳定性、功效和毒性仍然是该领域研究人员面临的挑战。本综述重点介绍了各种类型的纳米粒子在生物医药中的最新进展，对材料科学、化学、生物学和医学领域的研究人员将具有重要价值。
