Kovacs G, Baker G, Burger H, De Kretser D, Lording D, Lee J
Reproductive Medicine Clinic, Prince Henry's Hospital, Melbourne, Australia.
Br J Obstet Gynaecol. 1988 Apr;95(4):354-60. doi: 10.1111/j.1471-0528.1988.tb06605.x.
Ten years' experience of artificial insemination with cryopreserved donor semen for 1023 courses in 783 women resulting in 572 pregnancies is reported. A simple approach with multiple inseminations timed on the basis of cycle length, temperature charts, mucus symptoms and signs was used. The life table pregnancy rate was 61% after 12 cycles of treatment and 75% after 24 cycles. Women had a significantly higher rate of pregnancy in second and subsequent courses of treatment, and the pregnancy rate for treatment beyond 12 cycles was significantly less successful. Women over 35 years of age were significantly less successful.
报告了783名女性接受1023个疗程冷冻供体精液人工授精的十年经验，共产生572例妊娠。采用了一种基于月经周期长度、体温图表、黏液症状和体征进行多次授精定时的简单方法。治疗12个周期后的生命表妊娠率为61%，24个周期后为75%。女性在第二次及后续治疗疗程中的妊娠率显著更高，超过12个周期的治疗妊娠率显著降低。35岁以上的女性成功率显著更低。
