DiMarzo S J, Huang J, Kennedy J F, Villanueva B, Hebert S A, Young P E
Fertility Institute, Infertility, Gynecology, and Obstetrics Medical Group of San Diego, Inc., CA 91212.
Am J Obstet Gynecol. 1990 Jun;162(6):1483-8; discussion 1488-90. doi: 10.1016/0002-9378(90)90910-y.
From late 1970 through December 1987, 580 women began 733 treatment programs (a total of 3405 insemination cycles) with fresh semen for artificial insemination by donor. The unadjusted pregnancy rate was 48.5% and the cumulative pregnancy rate after seven cycles by life-table analysis was 59.6% with a monthly fecundability of 11.9%. From 1988 to the present, 113 women have begun 115 treatment programs (a total of 371 insemination cycles) with cryopreserved semen for artificial insemination by donor. The unadjusted pregnancy rate to date is 18.3% and the cumulative pregnancy rate after seven cycles by life-table analysis is 48.6% with a monthly fecundability of 5.9%. This report shows that using cryopreserved semen for artificial insemination by donor will take somewhat longer to produce a pregnancy but the ultimate pregnancy rate will be similar to that with fresh semen for artificial insemination by donor.
从1970年末到1987年12月，580名女性开始了733个使用新鲜精液进行供体人工授精的治疗项目（总共3405个授精周期）。未经调整的妊娠率为48.5%，通过寿命表分析，七个周期后的累积妊娠率为59.6%，每月受孕能力为11.9%。从1988年至今，113名女性开始了115个使用冷冻精液进行供体人工授精的治疗项目（总共371个授精周期）。迄今为止，未经调整的妊娠率为18.3%，通过寿命表分析，七个周期后的累积妊娠率为48.6%，每月受孕能力为5.9%。本报告表明，使用冷冻精液进行供体人工授精产生妊娠的时间会稍长一些，但最终妊娠率将与使用新鲜精液进行供体人工授精的妊娠率相似。
