68Ga-PSMA PET/CT 扫描在鼻窦血管外皮细胞瘤术后评估中的应用。

68Ga-PSMA PET/CT Scan on Postoperative Assessment of Sinonasal Glomangiopericytoma.

机构信息

From the Departments of Otorhinolaryngology & Head and Neck Surgery.

Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Clin Nucl Med. 2021 Sep 1;46(9):e478-e479. doi: 10.1097/RLU.0000000000003644.

DOI:10.1097/RLU.0000000000003644

PMID:33826565

Abstract

Prostate-specific membrane antigen (PSMA) is expressed on the endothelial cells of tumor-associated neovasculature of various nonprostatic benign and malignant neoplasms. Positive intense uptake on PET/CT imaging with 68Ga-labeled PSMA is noted in a patient with sinonasal glomangiopericytoma, and the same is noted to be absent following complete surgical excision. 68Ga-PSMA PET/CT may be a useful tool for early recurrence identification, differentiating recurrence from surgical site reparative tissues, and peptide receptor radionuclide therapy of residual lesions.

摘要

前列腺特异性膜抗原（PSMA）表达于各种非前列腺良性和恶性肿瘤相关新生血管的内皮细胞上。一位鼻窦血管外皮细胞瘤患者的 PET/CT 成像显示 68Ga 标记的 PSMA 摄取阳性且强烈，而在完全手术切除后则未见摄取。68Ga-PSMA PET/CT 可能是一种有用的工具，可用于早期复发的识别，区分复发与手术部位修复组织，并对残留病变进行肽受体放射性核素治疗。