68Ga-前列腺特异性膜抗原 PET/CT 扫描在青少年鼻腔血管纤维瘤术后评估中的临床应用。

Clinical Utility of 68Ga-Prostate-Specific Membrane Antigen PET/CT Scan on Postoperative Assessment of Juvenile Nasal Angiofibroma.

机构信息

From the Departments of Otorhinolaryngology and Head and Neck Surgery.

Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Clin Nucl Med. 2020 Feb;45(2):e83-e84. doi: 10.1097/RLU.0000000000002745.

DOI:10.1097/RLU.0000000000002745

PMID:31348086

Abstract

Prostate-specific membrane antigen (PSMA) is expressed on the endothelial cells of tumor-associated neovasculature of various nonprostatic benign and malignant neoplasms. Positive uptake on PET/CT imaging with Ga-labeled PSMA is noted in a patient with juvenile nasal angiofibroma, and the same is noted to be absent following complete surgical excision. Ga-PSMA PET/CT may be a useful tool for juvenile nasal angiofibroma recurrence identification and in differentiating recurrence from surgical site reparative tissue.

摘要

前列腺特异性膜抗原（PSMA）表达于多种非前列腺良、恶性肿瘤相关新生血管的内皮细胞上。Ga 标记 PSMA 的 PET/CT 成像显示，在患有青少年鼻血管纤维瘤的患者中可见阳性摄取，而在完全手术切除后则未见摄取。Ga-PSMA PET/CT 可能是青少年鼻血管纤维瘤复发识别和区分复发与手术部位修复组织的有用工具。