Kozlov V I, Tupitsyn I O, Litvin F B
Biull Eksp Biol Med. 1988 May;105(5):520-2.
Changes in microvascular reactivity in pia mater system have been studied under conditions of bilateral occlusion of common carotid arteries in rats of different age groups. The studies were performed on the 7th, 30th, 45th and 90th day of the postnatal development. The occlusion of common carotid arteries lasted 6 min in week-old animals and 9 min in rats of other age groups. The phase character of microvascular reactivity has been determined. It has been found that dilation of arterioles depends on the age of the animal. So dilation of precortical arterioles averaged 20-25% of the initial level in 7-day-old animals and increased to 60-75% in 30- and 45-day-old animals. It has been determined that the smaller is the diameter of the vessels the more expressed is their reactivity. It has been shown that a steady reaction of compensatory adaptation in microvessels in characteristic only of adult animals.
在不同年龄组的大鼠双侧颈总动脉闭塞的条件下，研究了软脑膜系统微血管反应性的变化。研究在出生后发育的第7天、第30天、第45天和第90天进行。一周龄动物的颈总动脉闭塞持续6分钟，其他年龄组的大鼠持续9分钟。已确定微血管反应性的阶段性特征。已发现小动脉的扩张取决于动物的年龄。因此，皮质前小动脉的扩张在7日龄动物中平均为初始水平的20%-25%，在30日龄和45日龄动物中增加到60%-75%。已确定血管直径越小，其反应性越明显。已表明微血管中代偿性适应的稳定反应仅在成年动物中具有特征性。
