Oral and Maxillofacial Surgery, Pinderfields Hospital, Mid Yorkshire Hospitals NHS Trust, Wakefield, UK
Oral and Maxillofacial Surgery, Pinderfields Hospital, Mid Yorkshire Hospitals NHS Trust, Wakefield, UK.
BMJ Case Rep. 2021 Apr 7;14(4):e239887. doi: 10.1136/bcr-2020-239887.
Neurofibromas are defined as benign tumours arising from peripheral nerve sheaths. Few intraoral palatal cases have been reported. Neurofibromas can occur as part of neurofibromatosis, type 1 (NF1) or type 2 (NF2). A 41-year-old patient presented with a slowly enlarging soft tissue mass on the hard palate. An incisional biopsy was performed, which confirmed the diagnosis of a neurofibroma associated with NF1. It should be considered that there is a chance of malignant transformation. Here, we discuss the clinical features, types, diagnosis, histopathology and treatment options.
神经纤维瘤被定义为起源于周围神经鞘的良性肿瘤。很少有口腔内腭部的病例报道。神经纤维瘤可作为神经纤维瘤病 1 型(NF1)或 2 型(NF2)的一部分发生。一名 41 岁的患者因硬腭上逐渐增大的软组织肿块就诊。进行了切开活检,证实诊断为与 NF1 相关的神经纤维瘤。应该考虑到有恶变的可能。在此,我们讨论其临床特征、类型、诊断、组织病理学和治疗选择。