Gel Potential of Red Onion ( L.) Ethanol Extract as Antifungal Cause Tinea Pedis.

INTRODUCTION

Tinea pedis is a dermatophyte infection of human feet, especially between the fingers and soles of the feet. Tinea pedis is caused by a fungal infection of . Red onion is one of the spices that has been widely known by the community and used as a traditional medicine in the prevention of fungus. The objective of this research was to determine the antifungal activity of gel produced from an extract of red onion on .

MATERIALS AND METHODS

The gel was formulated with various concentration of red onion, FI with a concentration of extract (5%), F2 (7.5%). and F3 (12.5%). Each formula tested the physical characteristics and antifungal activity toward . The antifungal activity was determined by the agar well-diffusion method using Saboround Dextrose Agar plates. Furthermore, the antifungal activities were assessed by the presence or absence of inhibition zones after the plates were incubated at 28C for 7 days.

RESULTS

F3 has the greatest inhibitory power than F1 and F2 ( < 0.05). Then, F3 has the same inhibitory power as a positive control ( > 0.05).

DISCUSSION

All gel understudy at various concentrations of red onion was formulated in gel-exhibited antifungal activity. Antifungal activity of red onion occurred because it contained allicin. Therefore, the researchers can use these gels as a natural antifungal in the healing of tinea pedis caused by .

CONCLUSION

The gel from an extract of red onion showed significant antifungal activity against