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骨闪烁显像的序贯评估:对血管化骨移植的分析

The sequential evaluation of bone scintigraphy: an analysis of revascularised bone grafts.

作者信息

Takato T, Harii K, Nakatsuka T

机构信息

Department of Plastic Surgery, Tokyo University Hospital, Japan.

出版信息

Br J Plast Surg. 1988 May;41(3):262-9. doi: 10.1016/0007-1226(88)90110-5.

DOI:10.1016/0007-1226(88)90110-5
PMID:3382853
Abstract

Technetium-99m Methylene Diphosphonate (Tc-99m MDP) has often been used to assess revascularisation of bone, because positive uptake of Tc-99m MDP reflects patent anastomoses and viability of the grafted bone. However, the sequential evaluation of bone scintigraphy has seldom been reported, especially in clinical cases. We carried out sequential evaluation in 17 patients with revascularised bone grafts. In this series, intense or maximal uptake in the grafted bone was observed in the early days after surgery (1-2 weeks postoperatively), with considerable reduction after 4 weeks. Furthermore, it was found that there was no uptake of Tc-99m MDP when the anastomosed vessels were occluded, even after 6 weeks, and these three cases all developed fracture or sequestrum. We therefore believe that bone scintigraphy is reliable in the postoperative monitoring of revascularised bone for at least 4 or 6 weeks postoperatively.

摘要

锝-99m亚甲基二膦酸盐(Tc-99m MDP)常被用于评估骨的血管重建,因为Tc-99m MDP的阳性摄取反映了移植骨吻合口通畅及存活情况。然而,骨闪烁显像的连续评估鲜有报道,尤其是在临床病例中。我们对17例血管重建骨移植患者进行了连续评估。在该系列中,术后早期(术后1-2周)在移植骨中观察到强烈或最大摄取,4周后摄取显著减少。此外,发现吻合血管闭塞时,即使在6周后Tc-99m MDP也无摄取,且这3例均发生骨折或死骨形成。因此,我们认为骨闪烁显像在术后至少4或6周对血管重建骨的监测中是可靠的。

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引用本文的文献

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Role of (99m)Tc-methylene diphosphonate bone scan in the evaluation of the viability of the bone flap in mandibular reconstruction in patients with oromaxillofacial malignancies.(99m)锝-亚甲基二膦酸盐骨扫描在评估口腔颌面恶性肿瘤患者下颌骨重建中骨瓣活力的作用
Indian J Nucl Med. 2015 Jul-Sep;30(3):280-2. doi: 10.4103/0972-3919.158549.
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Early postoperative bone scintigraphy in the evaluation of microvascular bone grafts in head and neck reconstruction.
术后早期骨闪烁显像在头颈部重建中微血管骨移植评估中的应用
Head Face Med. 2007 Apr 20;3:20. doi: 10.1186/1746-160X-3-20.
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Bone scintigraphy in the evaluation of bone grafts used for mandibular reconstruction.
Eur J Nucl Med. 1994 Feb;21(2):113-7. doi: 10.1007/BF00175757.